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Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance

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  • Additional Information
    • Contributors:
      Centre de résonance magnétique biologique et médicale (CRMBM); Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS); Nutrition, obésité et risque thrombotique (NORT); Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM); Génétique et immunologie des maladies parasitaires (GIMP); Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS); Service d'Endocrinologie, Maladies Métaboliques et de la Nutrition; Hôpital Nord CHU - APHM; Assistance Publique - Hôpitaux de Marseille (APHM); ANR-11-INBS-0006,FLI,France Life Imaging(2011)
    • Publication Information:
      HAL CCSD
      BioMed Central
    • Publication Date:
      2015
    • Collection:
      Aix-Marseille Université: HAL
    • Abstract:
      International audience ; Cardiovascular complications of obesity and diabetes are major health problems. Assessing their development, their link with ectopic fat deposition and their flexibility with therapeutic intervention is essential. The aim of this study was to longitudinally investigate cardiac alterations and ectopic fat accumulation associated with diet-induced obesity using multimodal cardiovascular magnetic resonance (CMR) in mice. The second objective was to monitor cardiac response to exendin-4 (GLP-1 receptor agonist).
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/26546347; hal-01414315; https://amu.hal.science/hal-01414315; https://amu.hal.science/hal-01414315/document; https://amu.hal.science/hal-01414315/file/AbdesselamJCMR2015.pdf; PRODINRA: 357227; PUBMED: 26546347; WOS: 000364186300001
    • Accession Number:
      10.1186/s12968-015-0198-x
    • Online Access:
      https://doi.org/10.1186/s12968-015-0198-x
      https://amu.hal.science/hal-01414315
      https://amu.hal.science/hal-01414315/document
      https://amu.hal.science/hal-01414315/file/AbdesselamJCMR2015.pdf
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • Accession Number:
      edsbas.11AEF178