Robust public computational services supporting Genome Assembly and Annotation for Australian researchers

Australian BioCommons is developing community-scale digital capacity, training and bioinformatics infrastructure to support Australia’s life scientists. We establish computational tools, systems and services with dedicated user support and provided at no cost to life scientists. Resources available to support genome assembly and annotation include: Galaxy Australia: provides over 60 freely available genome assembly and annotation tools/packages, resourced to achieve a eukaryotic genome assembly in < 2 hours and optimised end to end workflows for assembly (usegalaxy.org.au); The Australian AlphaFold Service: enables prediction of 3D protein structure from amino acid sequences using AI (biocommons.org.au/alphafold); The FGENESH++ Service: provides access and support to the FGENESH++ pipeline for eukaryotic genome annotation (biocommons.org.au/fgenesh-plus-plus); The Australian Apollo Service: provides a fully hosted virtual instance of the software, Apollo, to store and display genomes, annotations and evidence files with options for collaborative annotation curation (apollo-portal.genome.edu.au/); The Australian BioCommons Leadership Share (ABLeS): provides access to computational resources and bioinformatics expertise for producing reference datasets, biocommons.org.au/ables); Discovery of relevant software and best practice workflows via ToolFinder (biocommons.org.au/tool-finder) and our WorkflowHub space (workflowhub.eu/programmes/8/workflows); The Australian NextFlow Tower Service: provides a command post to manage and monitor bioinformatic pipelines across infrastructures and cloud providers of choice (australianbiocommons.github.io/tower/), and; Bioinformatics training materials, infrastructure and events through the National Training Program (biocommons.org.au/webinars-workshops). For more information and access to the services, visit biocommons.org.au. ; Presented at the International Congress of Genetics, Melbourne, 17th to 21st July 2023