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Unprecedented incorporation of α-emitter radioisotope 213Bi into porphyrin chelates with reference to a daughter isotope mediated assistance mechanism.

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  • Additional Information
    • Contributors:
      Institut des Sciences Chimiques de Rennes (ISCR); Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS); Laboratoire d'Analyses, d'Essais et d'Environnement (LAEE); Université Sidi Mohamed Ben Abdellah (USMBA); Centre de Recherche en Cancérologie Nantes-Angers (CRCNA); Université d'Angers (UA)-Centre Hospitalier Universitaire d'Angers (CHU Angers); PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE); Université de Nantes (UN)-Université de Nantes (UN); Signalisation et Réponses aux Agents Infectieux et Chimiques (SeRAIC); Université de Rennes (UR); JRC Institute for Transuranium Elements Karlsruhe (ITU ); European Commission - Joint Research Centre Karlsruhe (JRC); CNRS; Région Bretagne; La Ligue
    • Publication Information:
      HAL CCSD
      Royal Society of Chemistry
    • Publication Date:
      2011
    • Collection:
      Université de Rennes 1: Publications scientifiques (HAL)
    • Abstract:
      International audience ; For the first time, α-emitter radioisotope (213)Bi has been incorporated into porphyrin chelates, with rates matching with the short period of the radionuclide. An in situ transmetalation mechanism involving the daughter isotope (209)Pb is expected to boost the (213)Bi radiolabeling process.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/21709892; hal-00682434; https://hal.science/hal-00682434; https://hal.science/hal-00682434/document; https://hal.science/hal-00682434/file/Unprecedented_incorporation.accepted.pdf; PUBMED: 21709892
    • Accession Number:
      10.1039/c1cc12455b
    • Online Access:
      https://hal.science/hal-00682434
      https://hal.science/hal-00682434/document
      https://hal.science/hal-00682434/file/Unprecedented_incorporation.accepted.pdf
      https://doi.org/10.1039/c1cc12455b
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • Accession Number:
      edsbas.1FDCF00A