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Comparison of Troponin-I Levels Before and After Cardiopulmonary Bypass in Diabetic and Nondiabetic Coronary Artery Patients: Research Article ; Diyabetik ve Nondiyabetik Koroner Arter Hastalarında Kardiyopulmoner Bypass Öncesi ve Sonrası Troponin-I Düzeylerinin Karşılaştırılması: Araştırma Makalesi

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  • Additional Information
    • Publication Information:
      BİŞAR AMAÇ
    • Publication Date:
      2023
    • Abstract:
      Objective: The aim of this study is to compare the Troponin-I levels before and after CPB in diabetic and nondiabetic coronary artery patients. Methods: The data of 20 diabetic and 20 nondiabetic patients who had undergone CPB-guided cardiac surgery for coronary artery disease were retrospectively included in the study. Diabetic patients were determined as group 1 and nondiabetic as group 2. The data of the two groups were compared and evaluated. Results: The descriptive data of the study groups were similar and there was no statistically significant difference (p>0.05). There was a significant difference between preoperative and postoperative Troponin I levels of diabetic and nondiabetic patients (p<0.05). Conclusion: In conclusion, preoperative and postoperative Troponin I levels increase after CPB in both diabetic and nondiabetic patients. However, this increase is higher in diabetic patients than in nondiabetic patients. We think that cardiac troponins may be predictors of the effect of CPB on the myocardium as well as the myocardial protection strategies (cardioplegia solutions, hypothermia, etc.) used during CPB. ; Giriş: Kardiyak troponin I (cTnI) miyokardiyal hasar için tanısal bir biyobelirteçtir. Amaç: Bu çalışmanın amacı diyabetik ve nondiyabetik koroner arter hastalarında KPB öncesi ve sonrası Troponin-I düzeylerinin karşılaştırılması hedeflenmektedir. Yöntem: Koroner arter hastalığı nedeniyle KPB eşliğinde kardiyak cerrahi geçirmiş 20 diyabetik ve 20 nondiyabetik hasta verisi retrospektif olarak çalışmaya dahil edildi. Diyabetik olanlar grup 1, nondiyabetik olanlar grup 2 olarak belirlendi. İki grubun verileri karşılaştırılarak değerlendirildi. Bulgular: Çalışma gruplarının tanımlayıcı verileri benzerdi ve istatistiksel olarak anlamlı fark yoktu (p>0,05). Diyabetik ve nondiyabetik olan hastaların preoperatif ile postoperatif Troponin I düzeyleri arasında anlamlı fark vardı (p<0,05). Sonuç: Sonuç olarak hem diyabetik hem de nondiyabetik olan hastaların preoperatif ile postoperatif ...
    • File Description:
      application/pdf
    • Relation:
      https://actamedicaruha.com/index.php/pub/article/view/6/4; https://actamedicaruha.com/index.php/pub/article/view/6
    • Accession Number:
      10.5281/zenodo.7749142
    • Online Access:
      https://actamedicaruha.com/index.php/pub/article/view/6
      https://doi.org/10.5281/zenodo.7749142
    • Rights:
      Copyright (c) 2023 Acta Medica Ruha ; https://creativecommons.org/licenses/by/4.0
    • Accession Number:
      edsbas.2C37B8D6