Abstract: To efficiently interact with their environment, bacteria often work in groups to solve complex tasks. Coordination of collective functions requires communication among the members of the group, a process typically referred to as quorum sensing (QS). Marine Vibrio species, including the major human pathogen Vibrio cholerae , have become a model to study the regulatory architecture underlying QS. In this review we summarize how V. cholerae employs QS to regulate virulence, biofilm formation, type-6-secretion, and phage interactions.
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