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Correlates of diabetic polyneuropathy of the elderly in Sub-Saharan Africa

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  • Additional Information
    • Contributors:
      Laboratoire de Mathématiques Informatique et Applications UR1_1 (LAMIA); Université des Antilles (UA); Université de Yaoundé I (UY1); Université des Montagnes Bangangté, Cameroun; Université de Douala; Bordeaux population health (BPH); Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)
    • Publication Information:
      CCSD
      Public Library of Science
    • Publication Date:
      2020
    • Collection:
      Université des Antilles (UAG): HAL
    • Abstract:
      International audience ; Background: Diabetic polyneuropathy is associated with significant physical disability among older adults. However, their frequency and correlates are not well known in the older adults in Sub-Saharan-Africa. The objectives were to evaluate the hospital-based prevalence of diabetic polyneuropathy and identify its correlates in older adults.Methods: Over a period of 5 months, a cross-sectional survey was carried out at Douala Laquintinie Hospital (DLH), a main reference hospital in Douala, the economic capital of Cameroon. Participants in our study group comprised all patients with type 2 diabetes, whatever the reason for their reporting to the hospital. Diabetic Polyneuropathy was defined according to a Diabetic Neuropathy Examination score > 3/16.Results: A total of 159 older adults with diabetes were examined during this recruitment period, among whom 106 (66.7%) were women. The mean age was 68.3 ± 6.5 years. Diabetes median duration was 108 months. For all patients assessed using the Diabetic Neuropathy Examination score, polyneuropathy was reported in 31.4%; among them, polyneuropathy proved symptomatic in 78% of them. Correlates of polyneuropathy were glycated hemoglobin (p = 0.049), HIV infection (p = 0.031) and albuminuria (p< 0.001), even after adjustment for age, gender and duration of diabetes.Conclusion: A third of older adults with diabetes who visited our hospital were diagnosed with prevalent diabetes-related polyneuropathy. It shows that early detection is required through routine screening and regular follow-up examinations in order to reduce the risk of disability and improve the quality of life in elderly diabetics.
    • Accession Number:
      10.1371/journal.pone.0240602
    • Online Access:
      https://hal.science/hal-03144231
      https://hal.science/hal-03144231v1/document
      https://hal.science/hal-03144231v1/file/BPH_PO_2020_Simo.pdf
      https://doi.org/10.1371/journal.pone.0240602
    • Rights:
      http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
    • Accession Number:
      edsbas.46CB2B68