Rast izbranih oportuno patogenih gliv na treh izbranih nevrotransmiterjih ; Growth of selected human opportunistic fungi on three selected neurotransmitters

Alzheimerjeva bolezen je v današnjem času ena izmed najpogostejših nevrodegenerativnih bolezni, njena pojavnost pa se še povečuje. Obstajajo številne raziskave, ki se ukvarjajo z vzroki za njen nastanek. Nekaj jih trdi, da imajo glive pomemben vpliv na nastanek te bolezni. Trenutno je premalo dokazov, ki bi to potrdili. Na osnovi dosedanjih raziskav še ni popolnoma jasno, ali so glive vzrok ali posledica Alzheimerjeve bolezni. V svoji diplomski nalogi sem preučevala rast 61 izbranih humanih oportuno patogenih gliv, ki so pripadale 19 rodovom in 56 vrstam na treh posameznih nevrotransmiterjih: glutamatu, gama- aminobutirični kislini in acetilholinu. Dokazala sem, da določene glive z nevrotropnimi lastnostmi dobro uspevajo na aktivnih nevrotransmiterjih. ; Alzheimer's disease is now one of the most common neurodegenerative diseases and its incidence is increasing. There are many studies dealing with the causes of the disease. Some of them state that fungi can cause the Alzheimer disease. Currently, there is insufficient evidence to establish with certainty that the fungi are the real reason for the occurrence of Alzheimer's disease. Today it is not yet clear whether the fungi are the cause or the consequence of Alzheimer's disease. In my thesis I investigated the growth of 61 strains of human opportunistic fungi, belonging to 19 genera and 56 species on three selected neurotransmitters: glutamate, gamma- aminobutyric acid and acetylcholine. I proved that certain fungi with neurotropic properties grow well on the active neurotransmitters.