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Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023

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  • Additional Information
    • Contributors:
      Stark, Benjamin A.; Decleene, Nicole K.; Desai, Emily C.; Hsu, Johnathan M.; Johnson, Catherine O.; Lara-Castor, Laura; Legrand, Kate E.; A, Prof Bhoomadevi; Aalipour, Mohammad Amin; Aalruz, Hasan; Abafita, Bedru J.; Abaraogu, Ukachukwu O.; Abavisani, Mohammad; Abbas, Nasir; Abbasi, Madineh; Abbasian, Mohammadreza; Abbastabar, Hedayat; Abd Al Magied, Abdallah H. A.; Elhafeez, Samar Abd; Abdelalim, Prof Ahmed; Abdelfattah, Omar M.; Abdel-Hameed, Prof Reda; Abdelnabi, Mahmoud; Wael M Abdel-Rahman, Prof; Abdi, Parsa; Abdisa, Wakgari Mosisa; Abdissa, Daba; Abdous, Arman; Abdullah, Mujahid; Abdullahi, Auwal; Abdykerimova, Kulmira; Abebe, Mesfin; Abedi, Aidin; Abedi, Armita; Abejew, Asrat Agalu; Abhilash, E. S.; Abiodun, Olugbenga Olusola; Abiodun, Prof Olumide; Kasem, Rahim Abo; Aboagye, Richard Gyan; Abohashem, Shady; Abolhassani, Hassan; Abonie, Ulric Sena; Aborode, Abdullahi Tunde; Abourashed, Nagah Mohamed; Abramov, Dmitry; Abreu, Lucas Guimarãe; Abtahi, Dariush; Abu Farha, Rana Kamal; Kende Abubakar, Aminu Kende; Abubakar, Ibrahim Jatau; Abu-Elala, Nermeen; Abu-Gharbieh, Eman; Abukhadijah, Hana J.; Aburuz, Salahdein; Abushanab, Dina; Acharya, Anirudh Balakrishna; Acharya, Apurba; Acharya, Swetha; Achore, Meshack; Adal, Ousman; Adams, Lisa C.; Adamu, Lawan Hassan; Adão, Rui; Addo, Isaac Yeboah; Adebayo, Oladimeji Muritala; Adebisi, Tajudeen Adesanmi; Adedia, David; Adedokun, Kamoru Ademola; Adegbile, Oluwatobi E.; Adegboye, Oyelola A.; Adegoke, Nurudeen A.; Adekanmbi, Victor; Adeleke, Olumide Thoma; Oluwaseun Adetunji, Charle; Adeyomoye, Olorunsola Israel; Adha, Rishan; Adhikari, Kishor; Adhikary, Ripon Kumar; Adikusuma, Wirawan; Parvar, Tanin Adl; Adnan, Mohd; Sakilah Adnani, Qorinah Estiningtya; Adoma, Prince Owusu; Adzigbli, Leticia Akua; Adzrago, David; Afifi, Ahmed M.; Afolabi, Habeeb Abiodun; Afrashteh, Fatemeh; Afrooghe, Arya; Afzal, Muhammad Sohail; Afzal, Saira; Agampodi, Suneth Buddhika; Agarwal, Dhiraj Motilal; Agarwal, Gina; Agarwal, Prerna; Ageru, Temesgen Anjulo; Aggarwal, Navidha; Aghajanian, Sepehr; Sobrinho, César Agostini
    • Publication Information:
      Elsevier Inc.
    • Publication Date:
      2025
    • Collection:
      Padua Research Archive (IRIS - Università degli Studi di Padova)
    • Abstract:
      Background: Cardiovascular diseases (CVDs) are the leading cause of mortality and are among the foremost causes of disability globally. CVD burden has continued to increase in most countries since 1990, with trends driven by changing exposures to harmful risk factors, population growth, and population aging. Objectives: We report estimates of global, national, and subnational CVD burden, including 18 subdiseases and 12 associated modifiable risk factors. We analyzed change in CVD burden from 1990 to 2023 and identified drivers of change including population growth, population aging, and risk factor exposure. Methods: The Global Burden of Disease (GBD) 2023 study, a multinational collaborative research study, quantified burden due to 375 diseases including CVD burden and identified drivers of change from 1990 to 2023 using all available data and statistical models. GBD 2023 estimated the population-level burden of diseases in 204 countries and territories from 1990 to 2023. Results: CVDs were the leading cause of disability-adjusted life years (DALYs) and deaths estimated in the GBD. As of 2023, there were 437 million (95% UI: 401 to 465 million) CVD DALYs globally, a 1.4-fold increase from the number in 1990 of 320 million (292 to 344 million). Ischemic heart disease, intracerebral hemorrhage, ischemic stroke, and hypertensive heart disease were the leading cardiovascular causes of DALYs in 2023 globally. As of 2023, age-standardized CVD DALY rates were highest in low and low-middle Socio-demographic Index (SDI) settings and lowest in high SDI settings. The number of CVD deaths increased globally from 13.1 million (95% UI: 12.2 to 14.0 million) in 1990 to 19.2 million (95% UI: 17.4 to 20.4 million) in 2023. The number of prevalent cases of CVD more than doubled since 1990, with 311 million (95% UI: 294 to 333 million) prevalent cases of CVD in 1990 and 626 million (95% UI: 591 to 672 million) prevalent cases in 2023 globally. A total of 79.6% (95% UI: 75.7% to 82.5%) of CVD burden is attributable to modifiable ...
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/40990886; info:eu-repo/semantics/altIdentifier/wos/WOS:001630601900021; volume:86; issue:22; firstpage:2167; lastpage:2243; numberofpages:77; journal:JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; https://hdl.handle.net/11577/3573891
    • Accession Number:
      10.1016/j.jacc.2025.08.015
    • Online Access:
      https://hdl.handle.net/11577/3573891
      https://doi.org/10.1016/j.jacc.2025.08.015
    • Rights:
      info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/
    • Accession Number:
      edsbas.5B9D8195