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Additional file 1 of Autophagy inhibition improves the targeted radionuclide therapy efficacy of 131I-FAP-2286 in pancreatic cancer xenografts ...

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  • Additional Information
    • Publication Information:
      figshare
    • Publication Date:
      2024
    • Collection:
      DataCite Metadata Store (German National Library of Science and Technology)
    • Abstract:
      Additional file 1: Figure S1. (A-B) Representative western blot image and the semi-quantification analysis of p62 expression in PANC-1 cells. I, Control; II, 131I-FAP-2286; III, 131I-FAP-2286 + indirect coculture with CAFs (1: 1); IV, 131I-FAP-2286 + indirect coculture with CAFs (1: 5). *P < 0.05, ***P < 0.001, ****P < 0.0001. Figure S2. Representative coronal (Cor) and transverse (Tra) images of 131I-FAP-2286 SPECT/CT at different time points in only-PANC-1 tumor xenograft-bearing nude mice. The dotted circle points the location of the tumor. Figure S3. Representative coronal (Cor) and transverse (Tra) images of free 131I SPECT/CT at different time points in pancreatic cancer xenograft-bearing nude mice with the co-injection of PANC-1 + CAFs. The dotted circle points the location of the tumor. Figure S4. Immunohistochemistry images of FAP and α-SMA expression in the xenograft tumors with PANC-1 + CAFs (A) and PANC-1 alone (B). ...
    • Relation:
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    • Accession Number:
      10.6084/m9.figshare.25231174
    • Online Access:
      https://doi.org/10.6084/m9.figshare.2523117410.1158/0008-5472.can-14-015510.1371/journal.pmed.100026710.1016/j.ijrobp.2005.05.02910.1186/s13045-022-01343-y10.1038/s41551-022-00949-410.1007/s00259-023-06211-610.1021/acs.molpharmaceut.1c0056610.1097/rlu.000000000000402110.1016/s2213-8587(17)30401-110.1186/s12967-022-03559-510.1007/s00259-023-06272-710.2967/jnumed.118.22446910.1007/s00259-022-05842-510.2967/jnumed.120.25919210.1158/1078-0432.ccr-23-004610.3390/ijms1701010210.1038/nrclinonc.2016.18310.1038/nrd.2017.2210.1016/j.ebiom.2017.02.01910.1038/s43018-022-00426-6
      https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Autophagy_inhibition_improves_the_targeted_radionuclide_therapy_efficacy_of_131I-FAP-2286_in_pancreatic_cancer_xenografts/25231174
    • Rights:
      Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode ; cc-by-4.0
    • Accession Number:
      edsbas.6ABD6B60