Abstract: M.Phil. ; Helical microswimmers inspired by the flagellar propulsion of E. coli bacteria can be propelled and steered under a rotating magnetic field. Owing to such superior capability of untethered remote control, they have been applied in biomedical field widely after various functionalization. This dissertation presents an alternative approach to depositing superparamagnetic nanoparticles on the surface of laser printed helical microswimmers through a self-assembly process. The fabricated magnetic microdevice with thicker deposition film can be actuated faster in a rotating magnetic field and the speed increases linearly with an increase of input field frequency till reaching the step-out frequency. ; To date, imaging and tracking is a critical challenge for in vivo application of magnetic micro/nanorobots. For better bioimaging in vivo, most helical microswimmers are able to be imaged and tracked by bonding fluorescence dye on them. ; Here, we report the fabrication of fluorescent helical microswimmers by coating with fluorescent magnetic nanoparticles via electrostatic interaction. The fluorescent magnetic nanoparticles synthesized by Stöber method can contain either an arbitrary species of fluorescent dye or carbon quantum dots. Meanwhile, they can be navigated and tracked by using multi-coil system on an inverted fluorescence microscope. The method of coating multifunctional nanoparticles on 3D-printed microdevices provides a facile and convenient route for realizing multifunctional helical microswimmers through a self-assembly process, which holds great promise for a variety of biomedical applications. ; 受大腸桿菌鞭毛運動管道的啟發，螺旋微型機器人可以在旋轉磁場中被驅動和控制方向。由於具有遠程控制的優越效能，它們在經過各種功能化處理後可廣泛應用於生物醫學領域。本文提出了一種通過自組裝過程在鐳射列印的螺旋微型機器人表面包覆超順磁性納米顆粒的方法。具有較厚納米顆粒沉積層的磁性微型機器人可以在旋轉磁場中更快地運動，並且速度隨著磁場頻率的新增而線性新增，直到達到失步頻率。 ; 迄今為止，成像和跟踪是磁性微/納米機器人的體內應用的關鍵挑戰。為了在體內更好地進行生物成像，大多數螺旋式微型機器人通過結合螢光染料實現其成像和跟踪。 ...
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