Abstract: Rapid antigen tests (RATs) are suitable for point-of -care testing, require no laboratory time and give immediate results. However, are RATs useful for detecting asymptomatic COVID-19 infection when compared with polymerase chain reaction (PCR) testing in healthcare settings? The aim of this study was to implement a reliable testing system utilising RATs to promptly detect COVID-19 infection in predominantly asymptomatic patients transferred from acute hospitals to a post-acute rehabilitation unit (PARU). RAT testing was carried out on all new admissions without a history of confirmed Covid-19 infection within three months of admission. PCR testing was carried out on all patients with a positive RAT for confirmation purposes. The cycle threshold (Ct) values of COVID-19 detected results on PCR testing were examined to determine the utility of the RATs. A total of 1,403 patients were transferred to the PARU from January to December 2023. The results of the study revealed an 85% accuracy of RATs with a 15% rate of false negative results at the time of admission. All patients that had a positive RAT at the time of admission also had a positive PCR test. This testing algorithm resulted in early detection and prompt isolation of positive cases reducing the likely spread of COVID-19 infection, hospital outbreaks and bed/ward closures. [Abstract copyright: Copyright © 2024 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.]
Relation: https://orca.cardiff.ac.uk/id/eprint/174151/1/Role%20of%20admission%20rapid%20antigen%20testing%20%28RATs%29%20for%20COVID-19%20on%20patients%20transferred%20from%20acute%20hospitals%20to%20a%20post-acute%20rehabilitation%20setting_.pdf; Gaffney, Ann, Smyth, Edmond G, Moore, Zena orcid:0000-0002-4692-9718 orcid:0000-0002-4692-9718, Patton, Declan, Connor, Tom O and Derwin, Rosemarie 2024. Role of admission rapid antigen testing (RATs) for COVID-19 on patients transferred from acute hospitals to a post-acute rehabilitation setting. American Journal of Infection Control , S0196-6553(24)00822-8. 10.1016/j.ajic.2024.10.031 https://doi.org/10.1016/j.ajic.2024.10.031 Item availability restricted. file
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