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Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae

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  • Additional Information
    • Publication Information:
      Oxford University Press
    • Publication Date:
      2019
    • Collection:
      Cardiff University: ORCA (Online Research @ Cardiff)
    • Abstract:
      The coordination of cell growth and cell division is a fundamental problem in biology. The experiments with unicellular algae of Zachleder et al. (2019) show that up-regulation of cyclin-dependent kinase (CDK) activity can drive cell progression even when biosynthesis is reduced, indicating that the main link between cell growth and cell division is CDK activity rather than overall biosynthesis. Understanding this coupling between cellular growth and CDK activity will be important not just in these algae, but also in higher plants.
    • File Description:
      application/pdf
    • Relation:
      https://orca.cardiff.ac.uk/id/eprint/119701/7/erz008.pdf; Jones, Angharad https://orca.cardiff.ac.uk/view/cardiffauthors/A226823J.html orcid:0000-0001-7493-9625 orcid:0000-0001-7493-9625 and Dewitte, Walter https://orca.cardiff.ac.uk/view/cardiffauthors/A1487017.html orcid:0000-0002-0606-1686 orcid:0000-0002-0606-1686 2019. Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae. Journal of Experimental Botany 70 (3) , pp. 731-377. 10.1093/jxb/erz008 https://doi.org/10.1093/jxb%2Ferz008 file https://orca.cardiff.ac.uk/id/eprint/119701/7/erz008.pdf
    • Accession Number:
      10.1093/jxb/erz008
    • Online Access:
      https://orca.cardiff.ac.uk/id/eprint/119701/
      https://doi.org/10.1093/jxb/erz008
      https://orca.cardiff.ac.uk/id/eprint/119701/7/erz008.pdf
    • Rights:
      cc_by
    • Accession Number:
      edsbas.864C8E03