Abstract: Objective. To determine the relative risk (RR) of non-fatal unintentional and violence-related injury associated with alcohol consumption in three emergency departments in Latin America (2001-2002). Material and Methods. Pair-matched case-crossover was used to obtain RR estimates for alcohol in non-fatal injuries among 447 patients in Argentina (A), 489 in Brazil (B) and 455 in Mexico (M). Intentional (violence) or unintentional (non-violence) injury status were the main outcomes Results. About 46% of violence-related cases involved alcohol (versus 11.5% for non-violence related cases). The risk of violence-related injury increased with drinking and had an OR = 15.0 (95% confidence interval (CI), 5.8-39.1), with an OR = 4.2 (CI = 2.7-6.5) for unintentional injuries. Conclusions. Increasing amounts of drinking may have pronounced consequences on the risk of triggering an injury, especially for a violence-related injury. The RR estimates provided here can be useful for new estimates on alcohol and the burden of disease. ; Inst Nacl Psiquiatria, Mexico City 14370, DF, Mexico ; Univ Autonoma Metropolitana, Mexico City 14370, DF, Mexico ; Univ Nacl Mar del Plata, Mar Del Plata, Argentina ; Univ Fed Sao Paulo, Alcohol Drug Res Unit, Sao Paulo, Brazil ; Inst Publ Hlth, Alcohol Res Grp, Berkeley, CA USA ; WHO, Dept Mental Hlth & Subst Dependence, CH-1211 Geneva, Switzerland ; Univ Fed Sao Paulo, Alcohol Drug Res Unit, Sao Paulo, Brazil ; Web of Science
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