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Development of Polymer Prosthetic Heart Valve - Fabrication and In Vitro Test- ; 고분자 인공 심장판막의 개발 -제작과 성능실험

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  • Additional Information
    • Contributors:
      김인영; 김종원; 정대영; 김철생; 민병구
    • Publication Information:
      Seoul National University College of Medicine
    • Publication Date:
      1991
    • Collection:
      Seoul National University: S-Space
    • Abstract:
      Prosthetic heart valves (PHV) with various types and materials have been developed and used until now, but PHVs have various problems that need improving. A new type of polymer PHV have been developed to ameliorate these problems. A hydrodynamic tester has also been developed for the precise evaluation of hydrodynamic performance of the developed PHV. PHV are composed of polyurethane, a material commonly used in biomedical materials because of its good biocompatibility and mechanical properties. To investigate its hydrodynamic properties, a trileaflet and bileaflet type polymer valve was fabricated. The results of comparative tests with the 2 polymer valves and a mechanical valve showed that the trileaflet polymer valve had a better hydrodynamic performance than the others. Though the bileaflet polymer valve showed a higher pressure drop and regurgitation than the trileaflet valve due to thicker leaflet flection of the bileaflet valve, if its fabrication method and design were corrected, a better result could be expected. For a study of the long-term stability of the PHV, accelerated endurance tests and stress analysis of PHVs are needed.
    • ISSN:
      0582-6802
    • Relation:
      Seoul J Med, Vol.32 No.1, pp. 35-42; http://hdl.handle.net/10371/6709
    • Online Access:
      http://hdl.handle.net/10371/6709
    • Accession Number:
      edsbas.9EF63CCD