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Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice.

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  • Additional Information
    • Contributors:
      HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.
    • Publication Date:
      2018
    • Collection:
      Helmholtz Centre of Infection Research (HZI), Braunschweig: Repository
    • Abstract:
      We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis
    • ISSN:
      1080-6059
    • Relation:
      http://hdl.handle.net/10033/621578
    • Accession Number:
      10.3201/eid2409.171825
    • Online Access:
      http://hdl.handle.net/10033/621578
      https://doi.org/10.3201/eid2409.171825
    • Rights:
      Attribution-NonCommercial-ShareAlike 3.0 United States ; http://creativecommons.org/licenses/by-nc-sa/3.0/us/
    • Accession Number:
      edsbas.A7EC7124