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Preventing antimalarial resistance with artemisinin-based combination therapy

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  • Author(s): Barnes, Karen I
  • Source:
    South African Journal for Continuing Medical Education ; http://www.cmej.org.za/index.php/cmej
  • Document Type:
    article in journal/newspaper
  • Language:
    English
  • Additional Information
    • Publication Information:
      Division of Clinical Pharmacology
      Faculty of Health Sciences
      University of Cape Town
    • Publication Date:
      2004
    • Collection:
      University of Cape Town: OpenUCT
    • Abstract:
      Malaria morbidity and mortality is rising, principally as a result of increasing antimalarial resistance. Resistance means that there is a shift to the right in the dose-response (concentration effect) relationship. Plasmodium falciparum has developed clinically significant resistance to all classes of antimalarial drugs, with the possible exception of artemisinin derivatives.
    • File Description:
      application/pdf
    • Relation:
      http://hdl.handle.net/11427/21528
    • Online Access:
      http://hdl.handle.net/11427/21528
    • Accession Number:
      edsbas.AED9C860