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Risk factors of suicide re-attempt: A two-year prospective study

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  • Additional Information
    • Contributors:
      Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier); Institut de Génomique Fonctionnelle (IGF); Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM); Fondation FondaMental Créteil; Institut des Neurosciences de Montpellier (INM); Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM); Université de Lorraine (UL); Institut Mondor de Recherche Biomédicale (IMRB); Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12); Hôpital Henri Mondor; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12); Fédération Hospitalo-Universitaire de Médecine de Précision en Psychiatrie = Addiction And Psychiatry Transformation with Precision Medicine Créteil, France (FHU ADAPT); Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); This study received financial support from the CHU Montpellier (PHRC UF 7653) and the Agence Nationale de la Recherche (NEURO 2007—GENESIS).; ANR-07-NEUR-0013,GENESIS,GEnétique, NEuropSychologie, Imagerie cérébrale fonctionnelle des conduites Suicidaires(2007)
    • Publication Information:
      HAL CCSD
      Elsevier
    • Publication Date:
      2024
    • Collection:
      Université de Lorraine: HAL
    • Abstract:
      International audience ; Background: History of suicide attempt (SA) is the strongest predictor of a new SA and suicide. It is primordial to identify additional risk factors of suicide re-attempt. The aim of this study was to identify risk factors of suicide re-attempt in patients with recent SA followed for 2 years.Methods: In this multicentric cohort of adult inpatients, the median of the index SA before inclusion was 10 days. Clinicians assessed a large panel of psychological dimensions using validated tools. Occurrence of a new SA or death by suicide during the follow-up was recorded. A cluster analysis was used to identify the dimensions that best characterized the population and a variable "number of personality traits" was created that included the three most representative traits: anxiety, anger, and anxious lability. Risk factors of re-attempt were assessed with adjusted Cox regression models.Results: Among the 379 patients included, 100 (26.4 %) re-attempted suicide and 6 (1.6 %) died by suicide. The two major risk factors of suicide re-attempt were no history of violent SA and presenting two or three personality traits among trait anxiety, anger and anxious lability.Limitations: It was impossible to know if treatment change during follow-up occur before or after the re-attempt.Discussion: One of the most important predictors of re-attempt in suicide attempters with mood disorders, was the presence of three personality traits (anger, anxiety, and anxious lability). Clinicians should provide close monitoring to patients presenting these traits and proposed treatments specifically targeting these dimensions, especially anxiety.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/38657762; PUBMED: 38657762
    • Accession Number:
      10.1016/j.jad.2024.04.058
    • Online Access:
      https://hal.science/hal-04570038
      https://hal.science/hal-04570038v1/document
      https://hal.science/hal-04570038v1/file/1-s2.0-S0165032724006621-main.pdf
      https://doi.org/10.1016/j.jad.2024.04.058
    • Rights:
      http://creativecommons.org/licenses/by-nc-nd/ ; info:eu-repo/semantics/OpenAccess
    • Accession Number:
      edsbas.BF921277