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Detection in and circulation of Bluetongue virus among domestic ruminants in Madagascar

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  • Additional Information
    • Contributors:
      Unité de Virologie Antananarivo, Madagascar (IPM); Institut Pasteur de Madagascar; Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP); Laboratoire de santé animale, sites de Maisons-Alfort et de Normandie; Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES); Unité d'Entomologie Médicale Antananarivo, Madagascar (IPM); Contrôle des maladies animales exotiques et émergentes (UMR CMAEE); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA); Institut Pasteur de Dakar; Réseau International des Instituts Pasteur (RIIP); This study was funded by an internal grant from IP Madagascar. Sera from cohort of cattle were obtained from study conducted in the frame of AnimalRisk-OI, a research program on emerging animal diseases in the Indian Ocean, funded by FEDER POCT (European Union, Regional Council of Reunion and French government). Sera from transversal study were obtained during survey of Rift valley fever funded by Word Health Organization and Food and Agriculture Organization through the Central Emergency Response Fund of the United Nations.
    • Publication Information:
      HAL CCSD
      Elsevier
    • Publication Date:
      2015
    • Collection:
      Institut National de la Recherche Agronomique: ProdINRA
    • Abstract:
      International audience ; So far, no published data was available concerning the circulation of Bluetongue virus (BTV) in Madagascar. During a survey on Rift Valley Fever, we were able to detect a virus belonging to BTV. Therefore, we conducted a study aiming at characterizing molecularly the BTV isolated and assess the importance of circulation of BTV in Madagascar. A total of 4393 sera from ruminants selected randomly by stratification and sampled in 30 districts of Madagascar were tested for BTV. Moreover, 175 cattle were followed during 11 months.Phylogenetic analyses were performed from virus isolated from unfed pools of mosquitoes.Overall, the estimated mean seroprevalence of infection at the national level was 95.9% (95% CI: [95.2–96.5]) in cattle and 83.7% (95% CI: [81.4–85.9]) in small ruminants. Estimation of incidence rate was 54 per 100 cattle-years assuming that the incidence rate is constant allyear along. Phylogenetic analyses revealed that BTV detected belong to serotype 2.In conclusion, our results showed that BTV is endemic in Madagascar and highly prevalent among cattle. In our study we did not work on the vector involved in transmission of BTV in cattle. Thus, research should be conducted to better describe epidemiology of BTV in Madagascar including vectors and assess economic impact of the disease associated to BTV infections.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/25736861; hal-01290712; https://hal.science/hal-01290712; https://hal.science/hal-01290712/document; https://hal.science/hal-01290712/file/Andriamandimby-2015-Bluetongue%20in%20Madagascar_Author%20file.pdf; PUBMED: 25736861
    • Accession Number:
      10.1016/j.vetmic.2015.02.009
    • Online Access:
      https://hal.science/hal-01290712
      https://hal.science/hal-01290712/document
      https://hal.science/hal-01290712/file/Andriamandimby-2015-Bluetongue%20in%20Madagascar_Author%20file.pdf
      https://doi.org/10.1016/j.vetmic.2015.02.009
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • Accession Number:
      edsbas.C2D25E51