Case Report: Severe Colonic Crohn Disease Initiated after Liver Transplantation Requiring Surgery

Introduction A patient using tacrolimus for hepatocyte transplantation (HT) was diagnosed with Crohn disease (CD) with mainly colonic involvement, despite drug immunosuppression due to the previous transplant. Upon routine colonoscopy, a lateral growth lesion was detected, which was endoscopically unresectable. Therefore, it was decided to perform a total colectomy with burial of the rectum and terminal ileostomy. During surgery, thickening of the terminal ileum and cecum was visualized, along with “fat-wrapping” and thickening of the entire mesocolon.