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Temperature-mortality associations by age and cause : a multi-country multi-city study

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  • Additional Information
    • Publication Information:
      Umeå universitet, Institutionen för folkhälsa och klinisk medicin
      Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, United States
      Environment and Health Modelling (EHM) Lab, Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, United Kingdom; Department of Statistics, Computer Science and Applications G. Parenti, University of Florence, Florence, Italy
      Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, United States; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States
      Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Oeschger Center for Climate Change Research, University of Bern, Bern, Switzerland
      Climate Research Foundation (FIC), Madrid, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
      Institute of Environmental Assessment and Water Research, Spanish Council for Scientific Research, Barcelona, Spain; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan
      School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan
      Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
      Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Climate, Air Quality Research Unit, School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia
      Center for Climate Change Adaptation, National Institute for Environmental Studies, Tsukuba, Japan
      Universidad de Buenos Aires, Facultad de Ciencias Sociales, Instituto de Investigaciones Gino Germani, Buenos Aires, Argentina
      Department of Pathology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
      INSPER, Sao Paulo, Brazil
      School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada; Environmental Health Science and Research Bureau, Health Canada, Ottawa, Canada
      Department of Environmental Health, School of Public Health, Fudan University, Shanghai, China
      Department of Environmental Health, University of Sao Paulo, Sao Paulo, Brazil
      Institute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic; Faculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czech Republic
      Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia
      Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland; Medical Research Center Oulu, MRC Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland
      Sante Publique France, Department of Environmental and Occupational Health, French National Public Health Agency, Saint Maurice, France
      Department of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Greece; School of Population Health and Environmental Sciences, King's College, London, United Kingdom
      Climatology Research Group, Institute of Landscape Ecology, University of Munster, Munster, Germany; Faculty of Geography and Environmental Sciences, Hakim Sabzevari University, Khorasan Razavi, Sabzevar, Iran
      Climate, Air Quality Research Unit, School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia
      Technological University, Dublin, Ireland
      Institute for Global Health, University College London, London, United Kingdom
      College of Health, Medicine and Life Sciences, Brunel University London, London, United Kingdom; Department of Epidemiology, Lazio Regional Health Service, Rome, Italy
      Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
      Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States
      Department of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
      Norwegian Institute of Public Health, Oslo, Norway
      Department of Environmental Health, Instituto Nacional de Saude Dr. Ricardo Jorge, Porto, Portugal; EPIUnit, Instituto de Saude Publica, Universidade Do Porto, Porto, Portugal; Laboratorio Para A Investigacao Integrativa e Translacional em Saude Populacional (ITR), Porto, Portugal
      Department of Earth Sciences, University of Torino, Turin, Italy
      Graduate School of Public Health, Seoul National University, Seoul, South Korea
      School of Biomedical Convergence Engineering, College of Information and Biomedical Engineering, Pusan National University, Yangsan, South Korea
      CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Department of Statistics and Computational Research, Universitat de Valencia, Valencia, Spain
      Swiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland
      Environmental and Occupational Medicine, National Taiwan University (NTU), College of Medicine, NTU Hospital, Taipei, Taiwan; National Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan
      Department of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam
      Environment and Health Modelling (EHM) Lab, Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, United Kingdom
    • Publication Date:
      2024
    • Collection:
      Umeå University: Publications (DiVA)
    • Abstract:
      Background: Heterogeneity in temperature-mortality relationships across locations may partly result from differences in the demographic structure of populations and their cause-specific vulnerabilities. Here we conduct the largest epidemiological study to date on the association between ambient temperature and mortality by age and cause using data from 532 cities in 33 countries. Methods: We collected daily temperature and mortality data from each country. Mortality data was provided as daily death counts within age groups from all, cardiovascular, respiratory, or noncardiorespiratory causes. We first fit quasi-Poisson regression models to estimate location-specific associations for each age-by-cause group. For each cause, we then pooled location-specific results in a dose-response multivariate meta-regression model that enabled us to estimate overall temperature-mortality curves at any age. The age analysis was limited to adults. Results: We observed high temperature effects on mortality from both cardiovascular and respiratory causes compared to noncardiorespiratory causes, with the highest cold-related risks from cardiovascular causes and the highest heat-related risks from respiratory causes. Risks generally increased with age, a pattern most consistent for cold and for nonrespiratory causes. For every cause group, risks at both temperature extremes were strongest at the oldest age (age 85 years). Excess mortality fractions were highest for cold at the oldest ages. Conclusions: There is a differential pattern of risk associated with heat and cold by cause and age; cardiorespiratory causes show stronger effects than noncardiorespiratory causes, and older adults have higher risks than younger adults.
    • File Description:
      application/pdf
    • Relation:
      2024, 8:5; Environmental Epidemiology, 2024, 8:5; PMID 39323989; ISI:001319335600001
    • Accession Number:
      10.1097/EE9.0000000000000336
    • Online Access:
      http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-231152
      https://doi.org/10.1097/EE9.0000000000000336
    • Rights:
      info:eu-repo/semantics/openAccess
    • Accession Number:
      edsbas.D512B45E