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Adoption of a pregnancy-specific intravenous insulin protocol (Pregnancy-IVI) at a regional centre has equivalent safety and efficacy outcomes as a tertiary hospital

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  • Additional Information
    • Contributors:
      The University of Newcastle. College of Health, Medicine and Wellbeing, School of Medicine and Public Health
    • Publication Information:
      John Wiley & Sons
    • Publication Date:
      2023
    • Collection:
      NOVA: The University of Newcastle Research Online (Australia)
    • Abstract:
      Women with diabetes in pregnancy (DIP) are at risk of hyperglycaemia during hospitalisation for administration of antenatal glucocorticoids, intercurrent illness and labour. Variable rate intravenous insulin (VRII) is commonly used to maintain maternal glucose at physiological levels, to minimise maternal ketoacidosis, fetal acidosis and neonatal hypoglycaemia. The Pregnancy-IVI is the most-studied VRII protocol, and has established efficacy and safety following betamethasone in gestational diabetes mellitus and pre-existing diabetes mellitus. However, implementation has only been reported at tertiary care hospitals, and it is unclear whether VRII can be safely implemented in secondary care hospitals in regional areas, particularly with reference to the risk of maternal hypoglycaemia.
    • ISSN:
      0742-3071
    • Relation:
      Diabetic Medicine Vol. 40, Issue 1, no. e15003; http://hdl.handle.net/1959.13/1481758; uon:50795
    • Online Access:
      http://hdl.handle.net/1959.13/1481758
    • Rights:
      © 2022 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
    • Accession Number:
      edsbas.DEAF0891