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In-vitro cardiovascular protective activity of a new achillinoside from Achillea alpina

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  • Additional Information
    • Publication Information:
      Sociedade Brasileira de Farmacognosia
    • Publication Date:
      2019
    • Collection:
      SciELO Brazil (Scientific Electronic Library Online)
    • Abstract:
      Achillinoside was isolated from methanol extract of Achillea alpina L., Asteraceae. The structure of the compound was characterized based on various spectrum data, including IR, HR-ESI-MS, 1D and 2D NMR. The cardiovascular protective effect of achillinoside was tested on H2O2-induced H9c2 cells. In our research, achillinoside could increase the cell viability dose-dependently in H2O2-induced H9c2 cells. In addition, the levels of caspase-3/9 cells were significantly decreased in H2O2 and achillinoside incubated H9c2 cells.
    • File Description:
      text/html
    • Online Access:
      http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000400445
    • Rights:
      info:eu-repo/semantics/openAccess
    • Accession Number:
      edsbas.F60599C2