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Hormone Replacement Therapy on the Postmenopausal Endometrium

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  • Author(s): Faculdade de Ciências Médicas da Santa Casa de São Paulo
  • Source:
    Comparative Effects of Drospirenone and Tibolone on the Postmenopausal Endometrium
    Klaassens AH, van Wijk FH, Hanifi-Moghaddam P, Sijmons B, Ewing PC, Ten Kate-Booij MJ, Kooi GS, Kloosterboer HJ, Blok LJ, Burger CW. Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen. Fertil Steril. 2006 Aug;86(2):352-61. doi: 10.1016/j.fertnstert.2005.12.077. Epub 2006 Jul 7.
    Lima SM, Reis BF, Yamada SS, Postigo S, Grande RM, Botogoski SR, Campaner AB, Hueb CK, Galvao MA. Effects of drospirenone/estradiol on steroid receptors and Bcl-2 in the postmenopausal endometrium. Climacteric. 2011 Oct;14(5):551-7. doi: 10.3109/13697137.2011.559604. Epub 2011 Apr 6.
    Campaner AB, Longo Galvao MA. Application of an easy and useful morphometric technique for immunohistochemistry counting. Gynecol Oncol. 2009 Jan;112(1):282-3. doi: 10.1016/j.ygyno.2008.08.012. Epub 2008 Oct 19. No abstract available.
    Kloosterboer HJ. Tissue-selectivity: the mechanism of action of tibolone. Maturitas. 2004 Aug 30;48 Suppl 1:S30-40. doi: 10.1016/j.maturitas.2004.02.012.
    Grady D, Gebretsadik T, Kerlikowske K, Ernster V, Petitti D. Hormone replacement therapy and endometrial cancer risk: a meta-analysis. Obstet Gynecol. 1995 Feb;85(2):304-13. doi: 10.1016/0029-7844(94)00383-O.
    Smith-Bindman R, Kerlikowske K, Feldstein VA, Subak L, Scheidler J, Segal M, Brand R, Grady D. Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 1998 Nov 4;280(17):1510-7. doi: 10.1001/jama.280.17.1510.
    Gokaslan H, Oktem O, Durmusoglu F, Eren F. Apoptosis in the endometrium of postmenopausal women receiving tibolone. Gynecol Obstet Invest. 2003;56(3):124-7. doi: 10.1159/000073624. Epub 2003 Sep 22.