Therapeutic effect of Traditional Chinese Medicine water-jar cupping therapy combined with Mecobalamin in the treatment of Qi deficiency and blood stasis type diabetic peripheral neuropathy (中药水罐联合甲钴胺治疗气虚血瘀型糖尿病周围神经病变效果观察)

Objective To investigate the effect of Traditional Chinese Medicine water-jar cupping therapy in the treatment of Qi deficiency and blood stasis type diabetic peripheral neuropathy (DPN). Methods A total of sixty patients with DPN admitted to the Department of Cardiovascular Medicine of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University from January 2022 to September 2022 were selected as the research subjects, and randomly divided into the treatment group (n=30) and the control group (n=30) by the random number table method. The control group was given oral administration of Mecobalamin, and the treatment group was given Traditional Chinese Medicine water-jar cupping therapy on the basis of Mecobalamin treatment. Both groups were treated for 2 weeks. The clinical efficacy of the two groups was compared, and the nerve symptoms, nerve reflexes and sensory functions of the patients were evaluated by the Toronto Clinical Scoring System (TCSS). The sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) of the limbs (median nerve, posterior tibial nerve, common peroneal nerve) were measured by the NDI-200 electromyography evoked potential instrument. Results The total effective rate of the treatment group was higher than that of the control group (P＜0. 05). The TCSS scores of both groups decreased (P＜0. 01), and the score of the treatment group was lower than that of the control group (P＜0. 05). The SNCV and MNCV levels of both groups were significantly improved compared with those before treatment, and the differences were statistically significant (P＜0. 01). Moreover, the improvement of SNCV and MNCV levels in the treatment group was more significant than that in the control group, and the difference was statistically significant (P＜0. 05). Conclusion Traditional Chinese Medicine water-jar cupping therapy for DPN can effectively improve the clinical symptoms of patients, with good efficacy, no adverse reactions, high safety, and simple operation, which is more suitable for promotion and application in primary medical institutions. (目的 观察中药水罐联合甲钴胺治疗气虚血瘀型糖尿病周围神经病变(DPN)的临床疗效。方法 选取2022年1月—9月首都医科大学附属北京中医医院心血管科病房收治的 60例DPN患者为研究对象, 采用随机数字表法分为治疗组(n=30)和对照组(n=30)。对照组给予甲钴胺基础治疗, 治疗组在甲钴胺治疗基础上给予中药水罐治疗。两组均持续治疗2周。评价两组临床疗效, 使用多伦多临床评分系统(TCSS)评估患者神经症状、神经反射及感觉功能, 采用NDI-200肌电图诱发电位仪测定四肢神经(正中神经、胫后神经、腓总神经)的感觉传导速度(SNCV)和运动传导速度(MNCV)。结果 治疗组总有效率高于对照组, 差异有统计学意义(P＜0. 05)。干预后两组TCSS评分均较干预前降低义(P＜0. 01), 且治疗组评分低于对照组义(P＜0. 05)。两组SNCV、MNCV水平较治疗前提高(P＜0. 01), 且治疗组较对照组SNCV、MNCV水平提高明显, 差异有统计学意义(P＜0. 05)。结论 中药水罐治疗DPN可有效改善患者临床症状, 且无不良反应, 安全性高, 同时操作简单, 更适宜在基层医疗机构中的推广和应用。)