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Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

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  • Additional Information
    • Publication Information:
      Nature Portfolio, 2017.
    • Publication Date:
      2017
    • Collection:
      LCC:Science
    • Abstract:
      Hand grip strength as a proxy of muscular fitness is a clinical predictor of mortality and morbidity. In a large-scale GWA study, the authors find 16 robustly associated genetic loci that highlight roles in muscle fibre structure and function, neuronal maintenance and nervous system signal transduction.
    • File Description:
      electronic resource
    • ISSN:
      2041-1723
    • Relation:
      https://doaj.org/toc/2041-1723
    • Accession Number:
      10.1038/ncomms16015
    • Accession Number:
      edsdoj.79d45da5079409b8be2da8ab36a65af