Abstract: One of the key factors in societal progress is the improvement and enhancement of individuals' psychological well-being. With increased psychological well-being, individuals gain the ability to solve problems and successfully overcome challenges. The aim of this study is to investigate the relationship between e-health literacy and psychological well-being among youth and adults in Shiraz, based on Neuman's Health Theory. This study employed a survey method, and the statistical population included all young and adult residents of Shiraz, Iran. Based on Cochran's formula, 600 individuals were selected through stratified random sampling. Data collection tools included questionnaires, and SPSS software was used for statistical analysis. The results indicated a significant relationship between e-health literacy and psychological well-being among both youth and adults in Shiraz. Additionally, multivariate regression analysis showed that the psychological well-being of youth and adults in Shiraz was similar, with no significant differences between the two groups. Based on the findings of this study and Neuman's Health Theory, the higher the level of e-health literacy in a society, the greater the psychological well-being of its individuals. Consequently, society and its members will experience less anxiety, stress, and preoccupation. Therefore, to enhance psychological well-being as a crucial dimension of health and a factor in societal progress, it is recommended to increase the use and improvement of e-health literacy with the help of community members and officials.
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