Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

ST-segment deviations during pacing-induced increased heart rate in patients without coronary artery disease.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Publisher Information:
      Anestesiologi och intensivvård Institutionen för folkhälsa och klinisk medicin 2005
    • Abstract:
      INTRODUCTION: In order to interpret ST-segment changes as an indicator of ischemia in patients with higher heart rates (HRs), the relation between ST-segment levels and HR needs to be well defined in subjects without coronary artery disease. METHODS: Eighteen patients with normal ECGs in the catheterization laboratory, after radiofrequency ablation of AV nodal re-entry tachycardia or an accessory pathway were included. Computerized online vectorcardiography (VCG) was performed during step-wise atrial pacing-induced increases in HR up to 150 beats min(-1) (bpm). The ST-vector magnitude (ST-VM) and the relative ST change vector magnitude (STC-VM) were analysed at the J point, J + 20 and J + 60 ms. RESULTS: There was no divergence in the course of ST-VM or STC-VM based on J point + 0, 20, or 60 ms during increasing HR. The STC-VM mean values increased progressively during increases in HR above 100 bpm, with an average increase in STC-VM of 15-20 microV per 10 bpm increases in HR. The ST-VM response during HR increases showed a heterogeneous and unpredictable pattern. CONCLUSION: The STC-VM increases linearly with rising HRs above 100 bpm. The STC-VM can exceed widely recognized ischemic thresholds during higher HRs in the absence of ischemia. The choice of J point time to ST-VM measurements as tested here is not important for the STC-VM relation to HR at these HR levels. Further clinical testing is needed to improve the diagnostic specificity of STC-VM measurements during increased HRs.
    • Subject Terms:
      Adult; Arrhythmias; Cardiac/*diagnosis/*physiopathology/therapy; Cardiac Pacing; Artificial/*methods; Coronary Disease/diagnosis/physiopathology/therapy; Female; Heart Rate; Humans; Male; Middle Aged; Statistics as Topic; Vectorcardiography/*methods; Article in journal; info:eu-repo/semantics/article; text
    • Accession Number:
      10.1111.j.1475-097X.2005.00613.x
    • Availability:
      Open access content. Open access content
      info:eu-repo/semantics/openAccess
    • Note:
      application/pdf
      English
    • Other Numbers:
      UPE oai:DiVA.org:umu-6814
      0000-0002-5325-2688
      doi:10.1111/j.1475-097X.2005.00613.x
      PMID 15972028
      Scopus 2-s2.0-21644442981
      808843009
    • Contributing Source:
      UPPSALA UNIV LIBR
      From OAIster®, provided by the OCLC Cooperative.
    • Accession Number:
      edsoai.ocn808843009
HoldingsOnline