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A RECOMBINANT MICROORGANISM FOR PRODUCING L-GLUTAMIC ACID AND A METHOD FOR PRODUCING L-GLUTAMIC ACID USING THE SAME

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  • Publication Date:
    October 12, 2023
  • Additional Information
    • Document Number:
      20230323413
    • Appl. No:
      18/025050
    • Application Filed:
      June 30, 2021
    • Abstract:
      The present disclosure relates to a L-glutamic acid-producing recombinant microorganism comprising a SbtA protein or a polynucleotide encoding the SbtA protein, and to a method for producing L-glutamic acid by using the same.
    • Assignees:
      CJ CHEILJEDANG CORPORATION (Seoul, KR)
    • Claim:
      1. A recombinant microorganism of the genus Corynebacterium producing L-glutamic acid, the recombinant microorganism comprising a SbtA protein or a polynucleotide encoding the SbtA protein.
    • Claim:
      2. The recombinant microorganism of claim 1, wherein the SbtA protein is derived from cyanobacteria.
    • Claim:
      3. The recombinant microorganism of claim 1, wherein the SbtA protein contains the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having at least 90% sequence identity therewith.
    • Claim:
      4. The recombinant microorganism of claim 1, wherein the recombinant microorganism of the genus Corynebacterium is Corynebacterium glutamicum.
    • Claim:
      5. The recombinant microorganism of claim 1, in which activity of OdhA protein is further weakened.
    • Claim:
      6. A method for producing L-glutamic acid, the method comprising culturing, in a medium, a recombinant microorganism of the genus Corynebacterium producing L-glutamic acid, the recombinant microorganism comprising an SbtA protein or a polynucleotide encoding the SbtA protein.
    • Claim:
      7. The method of claim 6, wherein the SbtA protein is derived from cyanobacteria.
    • Claim:
      8. The method of claim 6, wherein the SbtA protein contains the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having at least 90% sequence identity therewith.
    • Claim:
      9. The method of claim 6, wherein the recombinant microorganism of the genus Corynebacterium is Corynebacterium glutamicum.
    • Claim:
      10. The method of claim 6, further comprising recovering L-glutamic acid from the recombinant microorganism or the medium.
    • Claim:
      11. The method of claim 6, wherein activity of OdhA protein is further weakened.
    • Current International Class:
      12; 07
    • Accession Number:
      edspap.20230323413