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Molecular Epidemiology of the HIV Epidemic in Three German Metropolitan Regions - Cologne/Bonn, Munich and Hannover, 1999-2016.

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  • Additional Information
    • Publication Information:
      eScholarship, University of California, 2018.
    • Publication Date:
      2018
    • Abstract:
      Using HIV sequence data to characterize clusters of HIV transmission may provide insight into the epidemic. Phylogenetic and network analyses were performed to infer putative relationships between HIV-1 partial pol sequences from 2,774 individuals receiving care in three German regions between 1999-2016. The regions have in common that they host some of the largest annual festivals in Europe (Carnival and Oktoberfest). Putative links with sequences (n = 150,396) from the Los Alamos HIV Sequence database were evaluated. A total of 595/2,774 (21.4%) sequences linked with at least one other sequence, forming 184 transmission clusters. Clustering individuals were significantly more likely to be younger, male, and report sex with men as their main risk factor (p
    • Accession Number:
      10.1038/s41598-018-25004-8
    • Rights:
      public
    • Accession Number:
      edssch.oai:escholarship.org:ark:/13030/qt6zs3t3q7