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Fatores associados ao óbito em casos confirmados de COVID-19 no estado do Rio de Janeiro.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      COVID-19/*epidemiology ; COVID-19/*mortality; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brazil/epidemiology ; COVID-19/diagnosis ; COVID-19/pathology ; Child ; Child, Preschool ; Cities/epidemiology ; Comorbidity ; Cross-Sectional Studies ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Mortality ; Prognosis ; Risk Assessment ; Risk Factors ; SARS-CoV-2/physiology ; Severity of Illness Index ; Socioeconomic Factors ; Survival Analysis ; Young Adult
    • Abstract:
      Background: COVID-19 can occur asymptomatically, as influenza-like illness, or as more severe forms, which characterize severe acute respiratory syndrome (SARS). Its mortality rate is higher in individuals over 80 years of age and in people with comorbidities, so these constitute the risk group for severe forms of the disease. We analyzed the factors associated with death in confirmed cases of COVID-19 in the state of Rio de Janeiro. This cross-sectional study evaluated the association between individual demographic, clinical, and epidemiological variables and the outcome (death) using data from the Unified Health System information systems.
      Methods: We used the extreme boosting gradient (XGBoost) model to analyze the data, which uses decision trees weighted by the estimation difficulty. To evaluate the relevance of each independent variable, we used the SHapley Additive exPlanations (SHAP) metric. From the probabilities generated by the XGBoost model, we transformed the data to the logarithm of odds to estimate the odds ratio for each independent variable.
      Results: This study showed that older individuals of black race/skin color with heart disease or diabetes who had dyspnea or fever were more likely to die.
      Conclusions: The early identification of patients who may progress to a more severe form of the disease can help improve the clinical management of patients with COVID-19 and is thus essential to reduce the lethality of the disease.
      (© 2021. The Author(s).)
    • Comments:
      Erratum in: BMC Infect Dis. 2021 Aug 2;21(1):728. (PMID: 34340676)
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    • Contributed Indexing:
      Keywords: COVID-19; Coronavirus death; Coronavirus infection; Machine learning; Pandemic; SARS-CoV-2; XGBoost
    • Publication Date:
      Date Created: 20210717 Date Completed: 20210721 Latest Revision: 20231107
    • Publication Date:
      20231215
    • Accession Number:
      PMC8283387
    • Accession Number:
      10.1186/s12879-021-06384-1
    • Accession Number:
      34271868