Risk of dengue, Zika, and chikungunya transmission in the metropolitan area of Cucuta, Colombia: cross-sectional analysis, baseline for a cluster-randomised controlled trial of a novel vector tool for water containers.

Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE

Original Publication: London : BioMed Central, [2001-

Dengue*/epidemiology ; Dengue*/prevention & control ; Chikungunya Fever*/epidemiology ; Chikungunya Fever*/prevention & control ; Zika Virus* ; Zika Virus Infection*/epidemiology ; Zika Virus Infection*/prevention & control ; Aedes*; Animals ; Humans ; Cross-Sectional Studies ; Water ; Colombia/epidemiology ; Mosquito Vectors ; Mosquito Control

Background: Arbovirus diseases such as dengue, Zika, and chikungunya are a public health threat in tropical and subtropical areas. In the absence of a vaccine or specific treatment, vector management (in this case the control of the primary vector Aedes aegypti) is the best practice to prevent the three diseases. A good understanding of vector behaviour, ecology, human mobility and water use can help design effective vector control programmes. This study collected baseline information on these factors for identifying the arbovirus transmission risk and assessed the requirements for a large intervention trial in Colombia.
Methods: Baseline surveys were conducted in 5,997 households, randomly selected from 24 clusters (neighbourhoods with on average 2000 houses and 250 households inspected) in the metropolitan area of Cucuta, Colombia. The study established population characteristics including water management and mobility as well as larval-pupal indices which were estimated and compared in all clusters. Additionally, the study estimated disease incidence from two sources: self-reported dengue cases in the household survey and cases notified by the national surveillance system.
Results: In all 24 study clusters similar social and demographic characteristics were found but the entomological indicators and estimated disease incidence rates varied. The entomological indicators showed a high vector infestation: House Index = 25.1%, Container Index = 12.3% and Breteau Index = 29.6. Pupae per person Index (PPI) as an indicator of the transmission risk showed a large range from 0.22 to 2.04 indicating a high transmission risk in most clusters. The concrete ground tanks for laundry -mostly outdoors and uncovered- were the containers with the highest production of Ae. aegypti as 86.3% of all 17,613 pupae were identified in these containers. Also, the annual incidence of dengue was high: 841.6 self-reported cases per 100,000 inhabitants and the dengue incidence notified by the National surveillance system was 1,013.4 cases per 100,000 in 2019. Only 2.2% of the households used container water for drinking. 40.3% of the study population travelled during the day (when Aedes mosquitoes bite) outside their clusters.
Conclusions: The production of Ae. aegypti mosquitoes occurred almost exclusively in concrete ground tanks for laundry (lavadero), the primary intervention target. The baseline study provides necessary evidence for the design and implementation of a cluster randomized intervention trial in Colombia.
(© 2023. The Author(s).)

BMC Public Health. 2017 May 30;17(Suppl 1):428. (PMID: 28699555)
PLoS Negl Trop Dis. 2017 Oct 12;11(10):e0005889. (PMID: 29023446)
Nat Microbiol. 2019 May;4(5):854-863. (PMID: 30833735)
Trans R Soc Trop Med Hyg. 2015 Feb;109(2):116-25. (PMID: 25604762)
Cad Saude Publica. 2009;25 Suppl 1:S93-103. (PMID: 19287871)
BMC Public Health. 2021 Jan 9;21(1):110. (PMID: 33422034)
Mem Inst Oswaldo Cruz. 2011 Sep;106(6):678-84. (PMID: 22012221)
Int J Environ Res Public Health. 2017 Feb 16;14(2):. (PMID: 28212349)
J Epidemiol Community Health. 2002 Feb;56(2):148-52. (PMID: 11812816)
Int J Infect Dis. 2021 Oct;111:271-280. (PMID: 34428546)
Pathog Glob Health. 2012 Dec;106(8):488-96. (PMID: 23318241)
Infect Dis Poverty. 2018 Jan 16;7(1):1. (PMID: 29335021)
Rev Chilena Infectol. 2015 Apr;32(2):142-9. (PMID: 26065446)
Med Vet Entomol. 1988 Apr;2(2):189-92. (PMID: 2980173)
Parasit Vectors. 2020 Oct 1;13(1):499. (PMID: 33004074)
Acta Trop. 1998 Jun 30;70(2):171-83. (PMID: 9698263)
Insects. 2022 Nov 17;13(11):. (PMID: 36421964)
BMJ. 2015 Jul 08;351:h3267. (PMID: 26156323)
Trans R Soc Trop Med Hyg. 2015 Feb;109(2):126-33. (PMID: 25604763)
PLoS Negl Trop Dis. 2020 Jan 16;14(1):e0007831. (PMID: 31945061)
PLoS Negl Trop Dis. 2016 Apr 21;10(4):e0004518. (PMID: 27101473)
J Vector Ecol. 2013 Jun;38(1):6-11. (PMID: 23701602)
Am J Trop Med Hyg. 2000 Jan;62(1):11-8. (PMID: 10761719)
Am J Trop Med Hyg. 2021 Oct 25;105(6):1786-1794. (PMID: 34695792)
Am J Trop Med Hyg. 2019 Jan;100(1):108-114. (PMID: 30426921)
Am J Trop Med Hyg. 2006 Feb;74(2):290-302. (PMID: 16474086)
J Med Entomol. 2007 Nov;44(6):930-7. (PMID: 18047190)
Rev Inst Med Trop Sao Paulo. 2020 Feb 07;62:e10. (PMID: 32049261)
N Engl J Med. 2016 Oct 20;375(16):1513-1523. (PMID: 27705091)
J Trop Med. 2021 Oct 23;2021:8483236. (PMID: 34725551)
Trop Med Health. 2011 Dec;39(4 Suppl):3-11. (PMID: 22500131)
Nature. 2014 Nov 13;515(7526):222-7. (PMID: 25391959)
Mem Inst Oswaldo Cruz. 2007 Jun;102(4):489-96. (PMID: 17612770)
Interdiscip Perspect Infect Dis. 2012;2012:907494. (PMID: 23056042)
Pathog Glob Health. 2012 Dec;106(8):428-35. (PMID: 23318234)
PLoS Negl Trop Dis. 2012;6(11):e1937. (PMID: 23209869)
Lancet Infect Dis. 2017 Mar;17(3):e101-e106. (PMID: 28011234)
J Med Entomol. 2011 Jan;48(1):45-52. (PMID: 21337947)
Int J Epidemiol. 2020 Jun 1;49(3):979-995. (PMID: 32087011)
PLoS One. 2017 Feb 22;12(2):e0172313. (PMID: 28225820)
Bull World Health Organ. 1970;43(2):319-25. (PMID: 5312528)
Trop Med Int Health. 2009 Sep;14(9):1143-53. (PMID: 19624476)
BMC Public Health. 2017 May 30;17(Suppl 1):450. (PMID: 28699559)
BMJ. 2009 Jun 09;338:b1959. (PMID: 19509031)
Salud Publica Mex. 2002 May-Jun;44(3):237-42. (PMID: 12132321)
Heliyon. 2019 Dec 31;6(1):e03101. (PMID: 31909268)
Am J Trop Med Hyg. 2022 Jul 5;:. (PMID: 35895401)
PLoS Negl Trop Dis. 2016 Sep 28;10(9):e0005016. (PMID: 27682141)
Am J Trop Med Hyg. 2014 Nov;91(5):1039-48. (PMID: 25223944)
Trans R Soc Trop Med Hyg. 2012 May;106(5):315-21. (PMID: 22465423)
Malar J. 2010 Nov 25;9:341. (PMID: 21108820)
PLoS Negl Trop Dis. 2016 May 26;10(5):e0004588. (PMID: 27227829)
Pathog Glob Health. 2012 Dec;106(8):479-87. (PMID: 23318240)
Rev Soc Bras Med Trop. 2008 Jan-Feb;41(1):79-81. (PMID: 18368277)
Biomedica. 2015 Apr-Jun;35(2):258-68. (PMID: 26535548)
PLoS Negl Trop Dis. 2019 Jun 10;13(6):e0007448. (PMID: 31181073)
J Am Mosq Control Assoc. 2015 Mar;31(1):77-84. (PMID: 25843179)
Cad Saude Publica. 2009;25 Suppl 1:S149-54. (PMID: 19287859)
J Econ Entomol. 2010 Apr;103(2):402-8. (PMID: 20429455)
Trop Med Parasitol. 1995 Dec;46(4):241-6. (PMID: 8826104)

Keywords: Aedes aegypti; Chikungunya; Dengue; Zika

059QF0KO0R (Water)

Date Created: 20230530 Date Completed: 20230601 Latest Revision: 20230602

20240105

PMC10227988

10.1186/s12889-023-15893-4

37254133