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The efficacy and safety of alternative treatments for menopausal symptoms in light of recent evidence ; Эффективность и безопасность альтернативных методов лечения менопаузальных симптомов в свете последних доказательных данных

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  • Additional Information
    • Publication Information:
      REMEDIUM GROUP Ltd.
    • Publication Date:
      2015
    • Collection:
      Medical Council (E-Journal) / Медицинский Совет
    • Abstract:
      Menopausal hormone therapy (MHT) is recognized as the most effective treatment of vaso-motor symptoms in women during menopausal transition and in postmenopause [1, 2]. Although various alternative therapies are widely used for this purpose, there is little sufficient evidence to support them. The market of the so-called natural plant preparations has been on the rise recently, although the effects of most of such preparations are not better than those of the placebo [3]. Many physicians and women mistakenly believe that absence of data on any adverse effects of alternative MHT medicines evidences their safety. [4] ; Менопаузальная гормональная терапия (МГТ) признана наиболее эффективным методом лечения вазомоторных симптомов у женщин в переходный период и в постменопаузе [1, 2]. Хотя с этой целью широко используются также различные альтернативные методы лечения, имеется недостаточно убедительных доказательств в их поддержку. За последние годы мы наблюдаем расцвет отрасли т. н. натуральных растительных препаратов, хотя эффективность большинства из них не превышает воздействие плацебо [3]. Многие врачи и женщины ошибочно полагают, что отсутствие данных о каком-либо неблагоприятном влиянии альтернативных МГТ-препаратов свидетельствует об их безопасности [4].
    • File Description:
      application/pdf
    • Relation:
      https://www.med-sovet.pro/jour/article/view/466/466; de Villiers TJ, Pines A, Panay N et al. Updated 2013 International Menopause Society recommendations on menopausal hormone therapy and preventive strategies for midlife health. Climacteric, 2013, 16: 316-337.; Practice Bulletin ACOG No. 141: Management of Menopausal Symptoms. Obstet Gynecol., 2014, 123: 202-216.; Geller SE, Shulman LP, van Breemen RB et al. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause, 2009, 16: 1156-1166.; Shulman LP. Has the pendulum begun to swing back? Menopause, 2014, 21(3): 211-2.; Manson JE. Current recommendations: what is the clinician to do? Fertil Steril., 2014, 101: 916-921.; Sternfeld B, LaCroix A, Caan BJ et aL Design and methods of a multi-site, multi-behavioral treatment trial for menopausal symptoms: the MsFLASH experience. Contemp Clin Trials, 2013, 35: 25-34.; Newton KM, Reed SD, Guthrie KA et al. Efficacy of yoga for vasomotor symptoms: a randomized controlled trial. Menopause, 2014, 21: 339-46.; Sternfeld B, Guthrie kA, Ensrud KE et al. Efficacy of exercise for menopausal symptoms: a randomized controlled trial. Menopause, 2014, 21: 330-8.; Cohen LS, Joffe H, Guthrie KA et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause, 2014, 21: 347-54; Reed SD, Guthrie KA, Newton KM et al. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements. Am J Obstet Gynecol, 2014, 210: 244; Mansikkamaki K, Raitanen J, Malila N, et al. Physical activity and menopause-related quality of life - A population-based cross-sectional study. Maturitas 2015, 80: 69-74.; Gold E, Colvin A, Avis N, et al. Longitudinal analysis of vasomotor symptoms and race/ethnicity across the menopausal transition: Study of Women's Health Across the Nation (SWAN). Am J Public Health 2006, 96: 1226-1235.; Thurston RC, Sowers MR, Sternfeld B, et al. Gains in body fat and vasomotor symptom reporting over the menopausal transition: the Study of Women's Health Across the Nation. Am J Epidemiol 2009, 170: 766-774.; Thurston RC, Ewing LJ, Low CA, et al. Behavioral weight loss for the management of menopausal hot flashes: a pilot study. Menopause 2015, 22(1): 59-65.; Gentry-Maharaj A, Karpinskyj C, Glazer C, et al. Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study. Menopause 2015, 22(4): 000/000. DOI:10.1097/gme.0000000000000330.; Chiu H-Y, Pan C-H, Shyu Y-K, et al. Effects of acupuncture on menopause-related symptoms and quality of life in women on natural menopause: a meta-analysis of randomized controlled trials. Menopause 2015, 22: 000/000. DOI:10.1097/gme.0000000000000260.; Freeman EW, Sammel, Sanders RJ. Risk of long-term hot flashes after natural menopause: evidence from the Penn Ovarian Aging Study cohort. Menopause 2014, 21(9): 924-32.; Taku K, Melby MK, Kronenberg F, et al. Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled trials. Menopause 2012, 19: 776-790.; Edena JA. Phytoestrogens for menopausal symptoms: A review. Maturitas 2012, 72: 157-159.; Amato P, Young RL, Steinberg FM, et al. Effect of soy isoflavone supplementation on menopausal quality of life. Menopause 2013, 20: 443-447.; Carmignani LO, Orcesi Pedro A, Montemor EB, et al. Effects of a soy-based dietary supplement compared with low-dose hormone therapy on the uro-genital system: a randomized, double-blind, controlled clinical trial. Menopause 2015, 22 (7): 000/000.DOI: 0.1097/gme.0000000000000380.; Lethaby A, Marjoribanks J, Kronenberg F, et al. Phytoestrogens for menopausal vasomotor symptoms. Cochrane Database Syst Rev 2013, 12. CD001395.; Gartoulla P, Han MM. Red clover extract for alleviating hot flushes in postmenopausal women: A meta-analysis Maturitas 2014, 79: 58-64.; Shike M, Doane AS, Russo L, et al. The Effects of Soy Supplementation on Gene Expression in Breast Cancer: A Randomized Placebo-controlled Study. J Natl Cancer Inst. 2014, 106(9).; Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD007244.; https://www.med-sovet.pro/jour/article/view/466
    • Accession Number:
      10.21518/2079-701X-2015-XX-14-19
    • Online Access:
      https://doi.org/10.21518/2079-701X-2015-XX-14-19
      https://doi.org/10.21518/2079-701X-2015-XX
      https://doi.org/10.1097/gme.0000000000000330
      https://doi.org/10.1097/gme.0000000000000260
      https://www.med-sovet.pro/jour/article/view/466
    • Rights:
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    • Accession Number:
      edsbas.E075142