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Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs.

• Authors : Periwal, Vinita^1,2 (AUTHOR); Bassler, Stefan^1,3 (AUTHOR); Andrejev, Sergej¹ (AUTHOR)

• Source: PLoS Computational Biology. 4/25/2022, Vol. 18 Issue 4, p1-21. 21p. 4 Graphs.

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Evaluation of a natural compound extracted from Dolichandrone atrovirens as a novel antioxidant agent using Caenorhabditis elegans.

• Authors : Yellurkar, Manoj Limbraj¹ (AUTHOR); Singh, Vibhavana^1,2 (AUTHOR); Sai Prasanna, Vani¹ (AUTHOR)

Subjects: *Caenorhabditis; *Caenorhabditis elegans; *Survival rate

• Source: PLoS ONE. 9/22/2021, Vol. 16 Issue 9, p1-14. 14p.

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The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression.

• Authors : Coulibaly, Anna¹; Haas, Astrid¹; Steinmann, Simone¹

Subjects: *Antineoplastic agents; *Gene regulatory networks; *Myeloid leukemia genetics

• Source: PLoS ONE. 2/2/2018, Vol. 13 Issue 2, p1-18. 18p.

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Computational study on new natural compound agonists of stimulator of interferon genes (STING).

• Authors : Zhong, Sheng^1,2; Li, Weihang³; Bai, Yang¹

• Source: PLoS ONE. 5/23/2019, Vol. 14 Issue 5, p1-17. 17p.

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A multi-targeting natural compound with growth inhibitory and anti-angiogenic properties re-sensitizes chemotherapy resistant cancer.

• Authors : Taylor, Wesley F.¹; Moghadam, Sara E.¹; Moridi Farimani, Mahdi²

Subjects: *Cancer chemotherapy; *Cell growth; *Developmental biologyUnited States

• Source: PLoS ONE. 6/11/2019, Vol. 14 Issue 6, p1-17. 17p.

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Trans,trans-farnesol, an antimicrobial natural compound, improves glass ionomer cement properties.

• Authors : de Castilho, Aline Rogéria Freire¹; Rosalen, Pedro Luiz²; de Souza Araújo, Isaac Jordão³

• Source: PLoS ONE. 8/20/2019, Vol. 14 Issue 8, p1-16. 16p.

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Control Effect and Possible Mechanism of the Natural Compound Phenazine-1-Carboxamide against Botrytis cinerea.

• Authors : Zhang, Ya^1,2; Wang, Chong³; Su, Pin⁴

Subjects: *Carboxamides; *Botrytis cinerea; *Pesticides

• Source: PLoS ONE. 10/13/2015, Vol. 10 Issue 10, p1-17. 17p.

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The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer.

• Authors : Fatima, Iram¹; El-Ayachi, Ikbale¹; Taotao, Ling²

Subjects: *Triple-negative breast cancer; *Estrogen receptors; *Progesterone receptors

• Source: PLoS ONE. 12/27/2017, Vol. 12 Issue 12, p1-18. 18p.

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Correction: Trans,trans-farnesol, an antimicrobial natural compound, improves glass ionomer cement properties.

• Authors : de Castilho ARF; Rosalen PL; de Souza Araújo IJ

• Source: PloS one [PLoS One] 2021 Oct 28; Vol. 16 (10), pp. e0259549. Date of Electronic Publication: 2021 Oct 28 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Differential Targeting of Unpaired Bases within Duplex DNA by the Natural Compound Clerocidin: A Valuable Tool to Dissect DNA Secondary Structure.

• Authors : Nadai, Matteo¹; Palù, Giorgio¹; Palumbo, Manlio²

Subjects: *DNA replication; *Nucleic acids; *Proteins

• Source: PLoS ONE. Dec2012, Vol. 7 Issue 12, p1-11. 11p.

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