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Academic Journal

Multiomics uncover the proinflammatory role of Trpm4 deletion after myocardial infarction in mice.

Authors : Boukenna, M.; Rougier, J.S.; Aghagolzadeh, P.

Subjects: Mice; Animals; Endothelial Cells/metabolism

Source: American journal of physiology. Heart and circulatory physiology, vol. 324, no. 4, pp. H504-H518

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Academic Journal

LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.

Authors : Bombaci, G.; Sarangdhar, M.A.; Andina, N.

Subjects: Animals; COVID-19/immunology; COVID-19/pathology

Source: Life science alliance, vol. 5, no. 6, pp. e202101226

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Academic Journal

Sulfur Amino Acid Supplementation Abrogates Protective Effects of Caloric Restriction for Enhancing Bone Marrow Regrowth Following Ionizing Radiation.

Authors : Hine, C.; Treviño-Villarreal, J.H.; Mejia, P.

Subjects: Animals; Bone Marrow/metabolism; Caloric Restriction

Source: Nutrients, vol. 14, no. 7, pp. 1529

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Academic Journal

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.

Authors : Smati, S.; Polizzi, A.; Fougerat, A.

Subjects: Animals; Diet; High-Fat/adverse effects

Source: Gut, vol. 71, no. 4, pp. 807-821

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Academic Journal

The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.

Authors : Domizio, J.D.; Gulen, M.F.; Saidoune, F.

Subjects: Animals; COVID-19/immunology; COVID-19/metabolism

Source: Nature, vol. 603, no. 7899, pp. 145-151

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Academic Journal

Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.

Authors : Ziros, P.G.; Renaud, C.O.; Chartoumpekis, D.V.

Subjects: Age Factors; Animals; Biomarkers/blood

Source: Thyroid, vol. 31, no. 1, pp. 23-35

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Academic Journal

GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.

Authors : Aguilar-Recarte, D.; Barroso, E.; Gumà, A.

Subjects: AMP-Activated Protein Kinases/metabolism; Adenylate Kinase/metabolism; Animals

Source: Cell reports, vol. 36, no. 6, pp. 109501

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Academic Journal

Methods for the Administration of EDAR Pathway Modulators in Mice.

Authors : Schuepbach-Mallepell, S.; Kowalczyk-Quintas, C.; Dick, A.

Subjects: Animals; Newborn; Disease Models

Source: Methods in molecular biology, vol. 2248, pp. 167-183

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Academic Journal

Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.

Authors : Lancien, M.; Gueno, L.; Salle, S.

Subjects: Adoptive Transfer/methods; Animals; CD8-Positive T-Lymphocytes/metabolism

Source: Cancer science, vol. 112, no. 5, pp. 1723-1734

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Academic Journal

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development.

Authors : Tenenbaum, M.; Plaisance, V.; Boutry, R.

Subjects: Animals; Cell Proliferation/drug effects; Cyclin D1/genetics

Source: Cellular and molecular life sciences, vol. 78, no. 1, pp. 287-298

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