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Academic Journal

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates

Authors : Reynard, Stéphanie; Gloaguen, Emilie; Baillet, Nicolas ...

Subjects: [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

Source: ISSN: 1935-2727.

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Academic Journal

Modeling favipiravir antiviral efficacy against emerging viruses: from animal studies to clinical trials

Authors : Madelain, Vincent; Mentré, France; Baize, Sylvain ...

Subjects: [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

Source: EISSN: 2163-8306 ; CPT: Pharmacometrics and Systems Pharmacology ; https://hal.science/hal-03131673 ; CPT: Pharmacometrics and Systems Pharmacology, 2020, 9 (5), pp.258-271. ⟨10.1002/psp4.12510⟩

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Academic Journal

Immune parameters and outcomes during Ebola virus disease

Authors : Reynard, Stéphanie; Journeaux, Alexandra; Gloaguen, Emilie ...

Subjects: Virology; Chemokines; Cytokines

Source: ISSN: 2379-3708 ; JCI Insight ; https://pasteur.hal.science/pasteur-02562418 ; JCI Insight, 2019, 4 (1), ⟨10.1172/jci.insight.125106⟩.

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Academic Journal

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

Authors : Madelain, Vincent; Baize, Sylvain; Jacquot, Frédéric ...

Subjects: MESH: Amides; MESH: Animals; MESH: Disease Models

Source: ISSN: 2041-1723.

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Academic Journal

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted

Authors : Nguyen, Thi Huyen Tram; Guedj, Jérémie; Anglaret, Xavier ...

Subjects: Pharmacokinetics; Creatinine; Viral load

Source: ISSN: 1935-2727.

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Academic Journal

Experimental treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial) : a historically controlled, single-arm proof-of-concept trial in Guinea

Authors : Sissoko, Daouda; Laouenan, Cedric; Folkesson, Elin ...

Subjects: Guinea; non-randomized trial; Ebola virus disease (EVD)

Source: ISSN: 1549-1277.

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