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An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light

• Authors : National Cancer Institute (NCI)

• Source: An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light

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Characterisation of TLR4+ Blood Cells in Patients With Solid Cancer (ODYSSEE)

• Source: Characterisation of TLR4+ Blood Cells in Patients With Solid Cancer

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TLR4 Polymorphisms and Risk of Skin Cancer

• Authors : Nabiha Yusuf, Associate Professor

• Source: TLR4 Polymorphisms and Predisposition for Skin Cancer Development

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TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries

• Authors : Gul Yildiz Telatar, Principal Investigator

• Source: Variants in Taste Genes on Caries Risk and Caries Activity StatusYildiz G, Ermis RB, Calapoglu NS, Celik EU, Turel GY. Gene-environment Interactions in the Etiology of Dental Caries. J Dent Res.

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A Phase I, 2-part (Part 1 Being a Single Dose Escalation and Part 2, a Parallel Group) Study of Toll-like Receptor (TLR4) Agonist (GSK1795091) in Healthy Subjects

• Source: A 2-part Randomized, Double-blind (Sponsor-unblinded), Placebo-controlled, Ascending Dose and Parallel Group Study of TLR4 Agonist (GSK1795091) Administered to Healthy

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MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by Surgery

• Authors : National Cancer Institute (NCI)

• Source: Peptide Vaccine With Glucopyranosyl Lipid A - Stable Oil-in-Water Emulsion (GLA-SE) for Patients With Resected Melanoma: A Pilot StudyKobayashi RH, Mandujano JF, Rehman SM, Kobayashi AL, Geng B,

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Role of TLR2 and TLR4 in Stage 2 Periodontitis Patients

• Authors : sudhir rama varma, Assistant Professor

• Source: Role of TLR2 and TLR4 in Stage 2 Periodontitis Patients With and Without Type 2 Diabetes

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TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma That Is Metastatic or Cannot Be Removed by Surgery

• Authors : National Cancer Institute (NCI)

• Source: A Phase I Study to Determine the Safety of the Combination of Stable-Emulsion Formulation of Glucopyranosyl Lipid A (GLA-SE) With Radiation in Patients With Metastatic SarcomaGoff PH, Riolobos

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The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects (Eritoran2)

• Source: Phase 2 Study of The Role of Pharmacologic Inhibition of TLR4 With E5564 on Glucose Metabolism in Insulin Resistant Subjects.Liang H, Sathavarodom N, Colmenares C,

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Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and Chemotherapy (ISILI)

• Source: ISILI (In Situ Immunotherapy of LIver Metastases): An Openlabel, Dose-finding, Phase I Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With

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