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Academic Journal

The antitumor antibiotic rebeccamycin—challenges and advanced approaches in production processes.

Authors : Pommerehne, Kathrin; Walisko, Jana; Ebersbach, Anna

Subjects: REBECCAMYCIN; PROCESS optimization; ANTINEOPLASTIC antibiotics

Source: Applied Microbiology & Biotechnology; May2019, Vol. 103 Issue 9, p3627-3636, 10p

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Academic Journal

XAD Resins for Increased Rebeccamycin Productivity in Cultivations of Lentzea aerocolonigenes.

Authors : Schrinner, Kathrin; Althof, Kristina; Ebersbach, Anna Theresia

Subjects: ANTINEOPLASTIC antibiotics; GLASS beads; PRODUCT recovery

Source: Chemie Ingenieur Technik (CIT); Jan2021, Vol. 93 Issue 1/2, p282-288, 7p

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Academic Journal

Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells.

Authors : Sun, Xiao; Lu, Zhanying; Liang, Zhenzhen

Subjects: TRIPLE-negative breast cancer; CANCER cells; BREAST cancer

Source: Molecules; Oct2022, Vol. 27 Issue 20, p6958-N.PAG, 15p

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Academic Journal

Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression.

Authors : Watari, Akihiro; Hasegawa, Maki; Yagi, Kiyohito

Subjects: EPITHELIAL cells; ENZYME activation; CLAUDINS

Source: PLoS ONE; 1/4/2016, Vol. 11 Issue 1, p1-19, 19p

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Academic Journal

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S-Adenosyl- L-Methionine Analogues.

Authors : Singh, Shanteri; Zhang, Jianjun; Huber, Tyler D.

Subjects: METHIONINE; TRANSFERASES; CARBAZOLE derivatives

Source: Angewandte Chemie; Apr2014, Vol. 126 Issue 15, p4046-4050, 5p

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Academic Journal

Characterization of the Biosynthetic Gene Cluster of Rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.

Authors : Onaka, Hiroyasu; Taniguchi, Shin-ichi; Igarashi, Yasuhiro

Subjects: CARBAZOLE; MICROCLUSTERS; ANTIBIOTICS

Source: Bioscience, Biotechnology & Biochemistry; Jan2003, Vol. 67 Issue 1, p127-138, 12p, 5 Diagrams, 3 Charts, 13 Graphs

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N-Glycoside of Indolo[2,3- a ]pyrrolo[3,4- c ]carbazole LCS1269 Exerts Anti-Glioblastoma Effects by G2 Cell Cycle Arrest and CDK1 Activity Modulation: Molecular Docking Studies, Biological Investigations, and ADMET Prediction.

Authors : Kalitin, Nikolay; Koroleva, Natalia; Lushnikova, Anna

Subjects: BINDING sites; MOLECULAR docking; CELL cycle

Source: Pharmaceuticals (14248247); Dec2024, Vol. 17 Issue 12, p1642, 20p

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Academic Journal

Morphological and physiological characterization of filamentous Lentzea aerocolonigenes: Comparison of biopellets by microscopy and flow cytometry.

Authors : Schrinner, Kathrin; Veiter, Lukas; Schmideder, Stefan

Subjects: FLOW cytometry; GLASS beads; MANUFACTURING processes

Source: PLoS ONE; 6/3/2020, Vol. 15 Issue 6, p1-19, 19p

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Academic Journal

Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives.

Authors : Sánchez, César; Méndez, Carmen; Salas, José A.

Subjects: NATURAL products; LEAD compounds; CANCER treatment

Source: Journal of Industrial Microbiology & Biotechnology; Jul2006, Vol. 33 Issue 7, p560-568, 9p, 8 Diagrams, 1 Chart

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Academic Journal

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S-Adenosyl- L-Methionine Analogues.

Authors : Singh, Shanteri; Zhang, Jianjun; Huber, Tyler D.

Subjects: SULFUR amino acids; CATALYSTS; METHIONINE

Source: Angewandte Chemie International Edition; Apr2014, Vol. 53 Issue 15, p3965-3969, 5p

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The antitumor antibiotic rebeccamycin—challenges and advanced approaches in production processes.

XAD Resins for Increased Rebeccamycin Productivity in Cultivations of Lentzea aerocolonigenes.

Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells.

Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression.

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S-Adenosyl- L-Methionine Analogues.

Characterization of the Biosynthetic Gene Cluster of Rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.

N-Glycoside of Indolo[2,3- a ]pyrrolo[3,4- c ]carbazole LCS1269 Exerts Anti-Glioblastoma Effects by G2 Cell Cycle Arrest and CDK1 Activity Modulation: Molecular Docking Studies, Biological Investigations, and ADMET Prediction.

Morphological and physiological characterization of filamentous Lentzea aerocolonigenes: Comparison of biopellets by microscopy and flow cytometry.

Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives.

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S-Adenosyl- L-Methionine Analogues.

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