Search Results

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

• Authors : Allaway, Robert; Angus, Steve P.; Beauchamp, Roberta L.

Subjects: Medicine and Health Sciences; Oncology; Cancers and Neoplasms

• Source: Allaway, R., S. P. Angus, R. L. Beauchamp, J. O. Blakeley, M. Bott, S. S. Burns, A. Carlstedt, et al. 2018. “Traditional and systems biology based drug

Record details

Open Source Drug Discovery in Practice: A Case Study

• Authors : Årdal, Christine; Rottingen, John-Arne

Subjects: Medicine; Drugs and Devices; Drug Research and Development

• Source: Årdal, Christine, and John-Arne Røttingen. 2012. Open source drug discovery in practice: A case study. PLoS Neglected Tropical Diseases

Record details

Novel Strategies for Drug Discovery Based on Intrinsically Disordered Proteins (IDPs)

• Authors : Wang, Jihua; Cao, Zanxia; Zhao, Liling

Subjects: intrinsically disordered proteins; sequence characterizations; structural characterizations

• Source: Wang, Jihua, Zanxia Cao, Liling Zhao, and Shuqiang Li. 2011. Novel strategies for drug discovery based on intrinsically disordered

Record details

Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus

• Authors : Rajamuthiah, Rajmohan; Fuchs, Beth Burgwyn; Kim, Younghoon

Subjects: Biology; Biotechnology; Drug discovery

• Source: Rajamuthiah, Rajmohan, Beth Burgwyn Fuchs, Elamparithi Jayamani, Younghoon Kim, Jonah Larkins-Ford, Annie Conery, Frederick M. Ausubel, and Eleftherios Mylonakis. 2014. “Whole Animal Automated

Record details

Genetics of rheumatoid arthritis contributes to biology and drug discovery

• Authors : Okada, Yukinori; Trynka, Gosia; Terao, Chikashi

• Source: Okada, Y., D. Wu, G. Trynka, T. Raj, C. Terao, K. Ikari, Y. Kochi, et al. 2013. “Genetics of rheumatoid arthritis contributes to biology and drug

Record details

The relative resistance of children to sepsis mortality: from pathways to drug candidates

• Authors : Joachim, Rose B; Altschuler, Gabriel M; Wong, Hector R

Subjects: Article; connectivity map; drug discovery

• Source: Joachim, Rose B, Gabriel M Altschuler, John N Hutchinson, Hector R Wong, Winston A Hide, and Lester Kobzik. 2018. “The relative resistance of children to sepsis mortality: from pathways to

Record details

Progress towards a public chemogenomic set for protein kinases and a call for contributions

• Authors : Drewry, David H.; Wells, Carrow I.; Andrews, David M.

Subjects: Biology and Life Sciences; Biochemistry; Enzymology

• Source: Drewry, D. H., C. I. Wells, D. M. Andrews, R. Angell, H. Al-Ali, A. D. Axtman, S. J. Capuzzi, et al. 2017. “Progress towards a public chemogenomic set for protein kinases and a call for

Record details

Microfluidic co‐culture devices to assess penetration of nanoparticles into cancer cell mass

• Authors : Jarvis, Maria; Arnold, Michael; Ott, Jenna

Subjects: drug delivery; drug discovery and development; microfludic device

• Source: Jarvis, Maria, Michael Arnold, Jenna Ott, Kapil Pant, Balabhaskar Prabhakarpandian, and Samir Mitragotri. 2017. “Microfluidic co‐culture devices to assess penetration of nanoparticles into cancer

Record details

Chemogenomics and orthology‐based design of antibiotic combination therapies

• Authors : Chandrasekaran, Sriram; Sahin, Nil; Yilancioglu, Kaan

Subjects: Article; chemogenomics; combination therapy

• Source: Chandrasekaran, Sriram, Melike Cokol‐Cakmak, Nil Sahin, Kaan Yilancioglu, Hilal Kazan, James J Collins, and Murat Cokol. 2016. “Chemogenomics and orthology‐based design of antibiotic combination

Record details

ksRepo: a generalized platform for computational drug repositioning

• Authors : Brown, Adam; Kohane, Isaac; Patel, Chirag

Subjects: Repositioning; Drug discovery; Prostate cancer

• Source: Brown, Adam S., Sek Won Kong, Isaac S. Kohane, and Chirag J. Patel. 2016. “ksRepo: a generalized platform for computational drug repositioning.” BMC Bioinformatics

Record details