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Academic Journal

In Silico Screening of Therapeutic Targets as a Tool to Optimize the Development of Drugs and Nutraceuticals in the Treatment of Diabetes mellitus : A Systematic Review.

Authors : Gomes, Ana Francisca T.¹ (NURSE) ; de Medeiros, Wendjilla F.¹ (NURSE) ; Medeiros, Isaiane² (NURSE)

Subjects: *DRUG development; *MOLECULAR dynamics; *DRUG target

Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9213. 15p.

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Academic Journal

Characterization of Three Novel 4-Methylaminorex Derivatives Applied as Designer Drugs.

Authors : Seibert, Elisabeth¹ (AUTHOR); Kunert, Olaf¹ (AUTHOR); Pferschy-Wenzig, Eva-Maria² (AUTHOR)

Subjects: *ULTRAVIOLET spectrometry; *DESIGNER drugs; *CHIRAL stationary phases

Source: Molecules. 9/15/2022, Vol. 27 Issue 18, p5770-N.PAG. 8p.

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Academic Journal

Construction of pioneering quantitative structure activity relationship screening models for abuse potential of designer drugs using index of ideality of correlation in monte carlo optimization.

Authors : Kumar, Ashwani¹ (AUTHOR) ; Kumar, Parvin² (AUTHOR)

Subjects: *STRUCTURE-activity relationships; *MONTE Carlo method; *DESIGNER drugs

Source: Archives of Toxicology. Sep2020, Vol. 94 Issue 9, p3069-3086. 18p. 5 Diagrams, 3 Charts, 3 Graphs.

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Academic Journal

Insights into the Silylation of Benzodiazepines Using N , O -Bis(trimethylsilyl)trifluoroacetamide (BSTFA): In Search of Optimal Conditions for Forensic Analysis by GC-MS.

Authors : Vargas Mena, Eleazar¹ (AUTHOR) ; Herrera Giraldo, Eliana R.² (AUTHOR) ; Gómez Castaño, Jovanny A.² (AUTHOR)

Subjects: *GAS chromatography/Mass spectrometry (GC-MS); *PSYCHIATRIC drugs; *PRINCIPAL components analysis

Source: Molecules. Dec2024, Vol. 29 Issue 24, p5884. 20p.

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Academic Journal

Recent advances in analysis of new psychoactive substances by means of liquid chromatography coupled with low-resolution tandem mass spectrometry.

Authors : Feigel, Bartłomiej^1,2 (AUTHOR) ; Adamowicz, Piotr¹ (AUTHOR); Wybraniec, Sławomir² (AUTHOR)

Subjects: *MASS spectrometry; *LIQUID chromatography-mass spectrometry; *LIQUID chromatography

Source: Analytical & Bioanalytical Chemistry. Jan2024, Vol. 416 Issue 1, p107-124. 18p.

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Academic Journal

Designer drugs: mechanism of action and adverse effects.

Authors : Luethi, Dino^1,2,3 (AUTHOR) ; Liechti, Matthias E.³ (AUTHOR)

Subjects: *SYNTHETIC marijuana; *DESIGNER drugs; *DRUG side effects

Source: Archives of Toxicology. Apr2020, Vol. 94 Issue 4, p1085-1133. 49p. 6 Diagrams, 3 Graphs.

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Academic Journal

The Dopaminergic Cells in the Median Raphe Region Regulate Social Behavior in Male Mice.

Authors : Chaves, Tiago^1,2,3 (AUTHOR) ; Török, Bibiána^1,2,3 (AUTHOR) ; Fazekas, Csilla Lea^1,2,3 (AUTHOR)

Subjects: *DOPAMINE receptors; *DOPAMINERGIC neurons; *DESIGNER drugs

Source: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4315. 22p.

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Academic Journal

In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach.

Authors : Dinger, Julia¹; Meyer, Markus¹; Maurer, Hans¹

Subjects: *CYTOCHROME P-450 regulation; *METHYLENEDIOXYPHENYL compounds; *DESIGNER drugs

Source: Archives of Toxicology. Feb2016, Vol. 90 Issue 2, p305-318. 14p. 2 Charts, 1 Graph.

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Academic Journal

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MS techniques.

Authors : Welter, Jessica¹; Brandt, Simon²; Kavanagh, Pierce³

Subjects: *DESIGNER drugs; *BENZOFURANS; *URINALYSIS

Source: Analytical & Bioanalytical Chemistry. May2015, Vol. 407 Issue 12, p3457-3470. 14p.

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Academic Journal

ELISA Detection of 30 New Amphetamine Designer Drugs in Whole Blood, Urine and Oral Fluid using Neogen® "Amphetamine" and "Methamphetamine/MDMA" Kits.

Authors : Nieddu, Maria¹; Burrai, Lucia¹ ; Baralla, Elena²

Subjects: *AMPHETAMINES; *DESIGNER drugs; *URINALYSIS

Source: Journal of Analytical Toxicology. Sep2016, Vol. 40 Issue 7, p492-497. 6p.

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In Silico Screening of Therapeutic Targets as a Tool to Optimize the Development of Drugs and Nutraceuticals in the Treatment of Diabetes mellitus : A Systematic Review.

Characterization of Three Novel 4-Methylaminorex Derivatives Applied as Designer Drugs.

Construction of pioneering quantitative structure activity relationship screening models for abuse potential of designer drugs using index of ideality of correlation in monte carlo optimization.

Insights into the Silylation of Benzodiazepines Using N , O -Bis(trimethylsilyl)trifluoroacetamide (BSTFA): In Search of Optimal Conditions for Forensic Analysis by GC-MS.

Recent advances in analysis of new psychoactive substances by means of liquid chromatography coupled with low-resolution tandem mass spectrometry.

Designer drugs: mechanism of action and adverse effects.

The Dopaminergic Cells in the Median Raphe Region Regulate Social Behavior in Male Mice.

In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach.

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MS techniques.

ELISA Detection of 30 New Amphetamine Designer Drugs in Whole Blood, Urine and Oral Fluid using Neogen® "Amphetamine" and "Methamphetamine/MDMA" Kits.

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