Search Results

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol.

• Authors : Ma L; Department of Immunology, School of Basic Medical Sciences, Binzhou Medical University, Yantai 264003, China.; Liu M

Subjects: Cannabidiol*/Cannabidiol*/Cannabidiol*/pharmacology ; Cannabidiol*/Cannabidiol*/Cannabidiol*/therapeutic use ; Cannabidiol*/Cannabidiol*/Cannabidiol*/chemistry

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 24; Vol. 29 (9). Date of Electronic Publication: 2024 Apr 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification.

• Authors : Li P; Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.; Wang D

Subjects: Silybin*/Silybin*/Silybin*/pharmacology ; Network Pharmacology* ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 22; Vol. 29 (8). Date of Electronic Publication: 2024 Apr 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.

• Authors : Li T; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.; Lv Q

Subjects: Ginkgo biloba* ; Insulin Resistance*; AMP-Activated Protein Kinases

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 03; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Rapid, Massive, and Green Synthesis of Polyoxometalate-Based Metal-Organic Frameworks to Fabricate POMOF/PAN Nanofiber Membranes for Selective Filtration of Cationic Dyes.

• Authors : Li J; College of Materials Science and Engineering, Jilin Institute of Chemical Technology, Jilin 132022, China.; Yu Z

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 27; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Transcriptome, Plant Hormone, and Metabolome Analysis Reveals the Mechanism of Purple Pericarp Formation in 'Zihui' Papaya ( Carica papaya L.).

• Authors : Wu X; Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Tropical and Subtropical Fruit Tree Research, Guangzhou 510640, China.; Yang M

Subjects: Carica*/Carica*/Carica*/genetics; Anthocyanins ; Plant Growth Regulators

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 27; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Fermentation Characteristics of Fermented Milk with Streptococcus thermophilus CICC 6063 and Lactobacillus helveticus CICC 6064 and Volatile Compound Dynamic Profiles during Fermentation and Storage.

• Authors : Zhao X; China Center of Industrial Culture Collection, China National Research Institute of Food and Fermentation Industries Co., Ltd., Beijing 100015, China.; Ge Y

Subjects: Lactobacillus helveticus* ; Lactobacillus delbrueckii*/Lactobacillus delbrueckii*/Lactobacillus delbrueckii*/metabolism ; Pentanones*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 12; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Nodakenin Ameliorates Ovariectomy-Induced Bone Loss by Regulating Gut Microbiota.

• Authors : Liu C; College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266000, China.; Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130117, China.

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/genetics ; Osteoporosis*/Osteoporosis*/Osteoporosis*/drug therapy ; Osteoporosis*/Osteoporosis*/Osteoporosis*/etiology

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 11; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

A Modified Tridecapeptide Probe for Imaging Cell Junction.

• Authors : Li J; School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.; Wu Y

Subjects: Connexin 43*/Connexin 43*/Connexin 43*/chemistry ; Connexin 43*/Connexin 43*/Connexin 43*/metabolism ; Gap Junctions*/Gap Junctions*/Gap Junctions*/metabolism

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 25; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Study on the Regeneration of Waste FCC Catalyst by Boron Modification.

• Authors : Yuan C; School of Materials Science and Engineering, Shandong University of Technology, Zibo 255000, China.; Chen Q

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 22; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Atractylenolide II Suppresses Glycolysis and Induces Apoptosis by Blocking the PADI3-ERK Signaling Pathway in Endometrial Cancer Cells.

• Authors : Tian S; Department of Pathology, College of Integrated Chinese and Western Medical, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.; Department of Cell Biology and Genetics, Basic Medical College, Jinzhou Medical University, Jinzhou 121001, China.

Subjects: Signal Transduction* ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/drug therapy ; Lactones*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 21; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

UHPLC-MS/MS Assay for Quantification of Legubicin, a Novel Doxorubicin-Based Legumain-Activated Prodrug, and Its Application to Pharmacokinetic and Tissue Distribution Studies.

• Authors : Ma L; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.

Subjects: Prodrugs*/Prodrugs*/Prodrugs*/chemistry ; Neoplasms* ; Cysteine Endopeptidases*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

The Graphene Quantum Dots Gated Nanoplatform for Photothermal-Enhanced Synergetic Tumor Therapy.

• Authors : Wang L; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.; Wang W

Subjects: Quantum Dots*/Quantum Dots*/Quantum Dots*/chemistry ; Graphite*/Graphite*/Graphite*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 27; Vol. 29 (3). Date of Electronic Publication: 2024 Jan 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Effects of Chalcogen Atoms on Excited-State Double-Proton Transfer Behavior for 3,6-bis(4,5-Dihydroxyoxazo-2-yl)benzene-1,2-diol Derivatives: A Computational Investigation.

• Authors : Yang D; College of Electronics and Engineering, North China University of Water Resources and Electric Power, Zhengzhou 450046, China.; Liu C

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 17; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Uncovering the Anti-Angiogenic Mechanisms of Centella asiatica via Network Pharmacology and Experimental Validation.

• Authors : Zhao B; Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.; Li Y

Subjects: Centella* ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology ; Neoplasms*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 11; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Palladium-Catalyzed β -C(sp 3 )-H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands.

• Authors : Xu Z; Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.; Li Z

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 03; Vol. 29 (1). Date of Electronic Publication: 2024 Jan 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Screening of Acetylcholinesterase Inhibitors by Capillary Electrophoresis with Oriented-Immobilized Enzyme Microreactors Based on Gold Nanoparticles.

• Authors : Zhang J; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.; Institute of Medicine, Xi'an Medical University, Xi'an 710021, China.

Subjects: Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/pharmacology ; Metal Nanoparticles*; Enzymes, Immobilized

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 24; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Rapid Screening of Phenolic Compounds with Anti-Enteritis Activity from Camellia oleifera Oil Using a Smurf Drosophila Model and Molecular Docking Methods.

• Authors : Wang S; Hunan Provincial Key Laboratory of Forest Edible Resources Safety and Processing Utilization, Central South University of Forestry and Technology, Changsha 410004, China.; Commodity Quality Inspection Institute of Hunan Province, Changsha 410004, China.

Subjects: Enteritis* ; Camellia*; Animals

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 22; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Optimized DOX Drug Deliveries via Chitosan-Mediated Nanoparticles and Stimuli Responses in Cancer Chemotherapy: A Review.

• Authors : Imran H; Department of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.; Tang Y

Subjects: Chitosan* ; Nanoparticles* ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 20; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Therapeutic Potential of Ginsenoside Rb1-PLGA Nanoparticles for Heart Failure Treatment via the ROS/PPARα/PGC1α Pathway.

• Authors : Du L; College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.; Lu H

Subjects: PPAR alpha* ; Heart Failure*/Heart Failure*/Heart Failure*/drug therapy; Rats

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 15; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Study on the Influence of CaO on the Electrochemical Reduction of Fe 2 O 3 in NaCl-CaCl 2 Molten Salt.

• Authors : Li H; Key Laboratory of Modern Metallurgical Technology, Ministry of Education, College of Metallurgy and Energy, North China University of Science and Technology, Tangshan 063210, China.; Song L

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 15; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Insight into the Inhibitory Mechanism of Embryonic Ectoderm Development Subunit by Triazolopyrimidine Derivatives as Inhibitors through Molecular Dynamics Simulation.

• Authors : Ju J; Institute of Theoretical Chemistry, College of Chemistry, Jilin University, 2 Liutiao Road, Changchun 130023, China.; Zhang H

Subjects: Molecular Dynamics Simulation* ; Ectoderm*/Ectoderm*/Ectoderm*/metabolism; Polycomb Repressive Complex 2/Polycomb Repressive Complex 2/Polycomb Repressive Complex 2/chemistry

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 07; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Chemical Constituents and α-Glucosidase Inhibitory, Antioxidant and Hepatoprotective Activities of Ampelopsis grossedentata .

• Authors : Luo QJ; TCM and Ethnomedicine Innovation & Development International Laboratory, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.; Zhou WC

Subjects: Ampelopsis*/Ampelopsis*/Ampelopsis*/chemistry ; Antioxidants*/Antioxidants*/Antioxidants*/pharmacology ; Antioxidants*/Antioxidants*/Antioxidants*/chemistry

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 05; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Identification of Dual-Target Inhibitors for Epidermal Growth Factor Receptor and AKT: Virtual Screening Based on Structure and Molecular Dynamics Study.

• Authors : Yang H; College of Physics, Qingdao University, Qingdao 266071, China.; Zhang Z

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Nov 15; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Elaiophylin Elicits Robust Anti-Tumor Responses via Apoptosis Induction and Attenuation of Proliferation, Migration, Invasion, and Angiogenesis in Pancreatic Cancer Cells.

• Authors : Huang L; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.; Liu Y

Subjects: Apoptosis* ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism; Humans

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 21; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details

Detection of Various Traditional Chinese Medicinal Metabolites as Angiotensin-Converting Enzyme Inhibitors: Molecular Docking, Activity Testing, and Surface Plasmon Resonance Approaches.

• Authors : Wu Q; Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.; Jiao Y

Subjects: Angiotensin-Converting Enzyme Inhibitors*/Angiotensin-Converting Enzyme Inhibitors*/Angiotensin-Converting Enzyme Inhibitors*/pharmacology ; Angiotensin-Converting Enzyme Inhibitors*/Angiotensin-Converting Enzyme Inhibitors*/Angiotensin-Converting Enzyme Inhibitors*/chemistry ; Biosensing Techniques*/Biosensing Techniques*/Biosensing Techniques*/methods

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 17; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

Record details