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Academic Journal

Genome-wide DNA methylation analysis identifies potent CpG signature for temzolomide response in non-G-CIMP glioblastomas with unmethylated MGMT promoter: MGMT-dependent roles of GPR81.

Authors : Liang BB; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.; Wang YH

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/genetics ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/radiotherapy

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Apr; Vol. 30 (4), pp. e14465. Date of Electronic Publication: 2023 Oct 13.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited

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Academic Journal

DNA methylation and chromatin accessibility predict age in the domestic dog.

Authors : Jin K; Department of Laboratory Medicine & Pathology, University of Washington, Seattle, Washington, USA.; McCoy BM

Subjects: DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Epigenesis, Genetic*; Dogs

Source: Aging cell [Aging Cell] 2024 Apr; Vol. 23 (4), pp. e14079. Date of Electronic Publication: 2024 Jan 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Epigenetic aging of human blood cells is influenced by the age of the host body.

Authors : Holland P; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Istre M

Subjects: Epigenesis, Genetic* ; DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/genetics

Source: Aging cell [Aging Cell] 2024 May; Vol. 23 (5), pp. e14112. Date of Electronic Publication: 2024 Mar 04.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

USP19 regulates DNA methylation damage repair and confers temozolomide resistance through MGMT stabilization.

Authors : Liu J; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA.

Subjects: Temozolomide*/Temozolomide*/Temozolomide*/pharmacology ; Temozolomide*/Temozolomide*/Temozolomide*/therapeutic use ; DNA Repair Enzymes*/DNA Repair Enzymes*/DNA Repair Enzymes*/metabolism

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Apr; Vol. 30 (4), pp. e14711.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium:

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Academic Journal

A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A Canadian Longitudinal Study on Aging analysis.

Authors : Verschoor CP; Health Sciences North Research Institute, Sudbury, Ontario, Canada.; Northern Ontario School of Medicine, Sudbury, Ontario, Canada.

Subjects: C-Reactive Protein*/C-Reactive Protein*/C-Reactive Protein*/metabolism ; DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics; Humans

Source: Aging cell [Aging Cell] 2023 Jul; Vol. 22 (7), pp. e13863. Date of Electronic Publication: 2023 May 04.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Region-based epigenetic clock design improves RRBS-based age prediction.

Authors : Simpson DJ; MRC Human Genetics Unit, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Zhao Q

Subjects: DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Epigenomics*; Mice

Source: Aging cell [Aging Cell] 2023 Aug; Vol. 22 (8), pp. e13866. Date of Electronic Publication: 2023 May 11.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

Authors : Tharakan R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

Subjects: Aging*/Aging*/Aging*/genetics ; DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics; Humans

Source: Aging cell [Aging Cell] 2023 Jul; Vol. 22 (7), pp. e13847. Date of Electronic Publication: 2023 Jun 12.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice.

Authors : Xu F; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.; Cong P

Subjects: Cognition Disorders*/Cognition Disorders*/Cognition Disorders*/metabolism ; DNA Methylation* ; Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/genetics

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 May; Vol. 29 (5), pp. 1229-1242. Date of Electronic Publication: 2023 Jan 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited

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Academic Journal

Alterations of the gut microbiome are associated with epigenetic age acceleration and physical fitness.

Authors : Torma F; Research Institute of Sport Science, Hungarian University of Sport Science, Budapest, Hungary.; Sports Neuroscience Division, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/genetics ; Microbiota*/Microbiota*/Microbiota*/genetics; Humans

Source: Aging cell [Aging Cell] 2024 Apr; Vol. 23 (4), pp. e14101. Date of Electronic Publication: 2024 Feb 27.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell-type deconvolution applied to human blood epigenetic clocks.

Authors : Zhang Z; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

Subjects: Acceleration* ; Arthritis, Rheumatoid*; Humans

Source: Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14071. Date of Electronic Publication: 2023 Dec 25.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Genome-wide DNA methylation analysis identifies potent CpG signature for temzolomide response in non-G-CIMP glioblastomas with unmethylated MGMT promoter: MGMT-dependent roles of GPR81.

DNA methylation and chromatin accessibility predict age in the domestic dog.

Epigenetic aging of human blood cells is influenced by the age of the host body.

USP19 regulates DNA methylation damage repair and confers temozolomide resistance through MGMT stabilization.

A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A Canadian Longitudinal Study on Aging analysis.

Region-based epigenetic clock design improves RRBS-based age prediction.

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice.

Alterations of the gut microbiome are associated with epigenetic age acceleration and physical fitness.

Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell-type deconvolution applied to human blood epigenetic clocks.