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Academic Journal

Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy.

Authors : Liu C; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.; Zhou F

Subjects: B7-H1 Antigen*/B7-H1 Antigen*/B7-H1 Antigen*/antagonists & inhibitors ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Programmed Cell Death 1 Receptor*/Programmed Cell Death 1 Receptor*/Programmed Cell Death 1 Receptor*/antagonists & inhibitors

Source: British journal of pharmacology [Br J Pharmacol] 2021 Jul; Vol. 178 (13), pp. 2651-2670. Date of Electronic Publication: 2021 May 04.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review).

Authors : Kong X; Integrated Traditional Chinese and Western Medicine Laboratory, College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China.; Lu P

Subjects: B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*genetics ; Immune Checkpoint Inhibitors/Immune Checkpoint Inhibitors/Immune Checkpoint Inhibitors/*therapeutic use ; Neoplasms/Neoplasms/Neoplasms/*therapy

Source: Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 24.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Implication of Ataxia-Telangiectasia-mutated kinase in epithelium-mesenchyme transition.

Authors : Miao T; Vascular Surgery of West China Hospital, Sichuan University, Chengdu, PR China.; Peng C

Subjects: Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/*genetics ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*genetics ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*genetics

Source: Carcinogenesis [Carcinogenesis] 2021 Apr 30; Vol. 42 (4), pp. 640-649.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

miR-200 affects tamoxifen resistance in breast cancer cells through regulation of MYB.

Authors : Gao Y; Department of General Surgery, Tianjin First Central Hospital, No.24, Fukang Road, Nankai District, Tianjin, 300204, China.; Zhang W

Subjects: Drug Resistance, Neoplasm* ; Epithelial-Mesenchymal Transition*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism

Source: Scientific reports [Sci Rep] 2019 Dec 11; Vol. 9 (1), pp. 18844. Date of Electronic Publication: 2019 Dec 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells.

Authors : Guo J; Institute of Biomedical Engineering and Health Sciences, Changzhou University, Changzhou 213164, China. .; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China. .

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Culture Media, Conditioned/Culture Media, Conditioned/Culture Media, Conditioned/*pharmacology ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2017 Aug 01; Vol. 18 (8). Date of Electronic Publication: 2017 Aug 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity.

Authors : Liu C; Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, Hubei 443001, P.R. China.; Lu J

Subjects: Gene Expression Regulation, Neoplastic* ; Immunomodulation*; B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*genetics

Source: Molecular medicine reports [Mol Med Rep] 2017 Mar; Vol. 15 (3), pp. 1063-1070. Date of Electronic Publication: 2017 Jan 05.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Prognostic and Clinicopathological Value of Programmed Death Ligand-1 in Breast Cancer: A Meta-Analysis.

Authors : Guo Y; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science And Technology, Wuhan, China.; Yu P

Subjects: B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*metabolism ; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology

Source: PloS one [PLoS One] 2016 May 26; Vol. 11 (5), pp. e0156323. Date of Electronic Publication: 2016 May 26 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells.

Authors : Liu Z; Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Ren L

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Cell Cycle/Cell Cycle/Cell Cycle/*drug effects

Source: PloS one [PLoS One] 2015 Jun 26; Vol. 10 (6), pp. e0131207. Date of Electronic Publication: 2015 Jun 26 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.

Authors : Ning Q; Department of Oncology, the First hospital Affiliated to School of Medicine of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.; Liu C

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*physiology ; Vascular Endothelial Growth Factor Receptor-1/Vascular Endothelial Growth Factor Receptor-1/Vascular Endothelial Growth Factor Receptor-1/*metabolism

Source: PloS one [PLoS One] 2013 Jun 11; Vol. 8 (6), pp. e65217. Date of Electronic Publication: 2013 Jun 11 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet

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Academic Journal

Efficacy and safety of pyrotinib combined with albumin-bound paclitaxel as first-line treatment for HER2-positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuvant trastuzumab therapy: The stage 1 results of a single-arm, phase 2 prospective clinical trial.

Authors : Man X; Department of Breast Medical Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.; Huang J

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Trastuzumab*/Trastuzumab*/Trastuzumab*/therapeutic use ; Trastuzumab*/Trastuzumab*/Trastuzumab*/pharmacology

Source: Clinical and translational medicine [Clin Transl Med] 2024 May; Vol. 14 (5), pp. e1687.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy.

A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review).

Implication of Ataxia-Telangiectasia-mutated kinase in epithelium-mesenchyme transition.

miR-200 affects tamoxifen resistance in breast cancer cells through regulation of MYB.

Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells.

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity.

Prognostic and Clinicopathological Value of Programmed Death Ligand-1 in Breast Cancer: A Meta-Analysis.

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells.

Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.

Efficacy and safety of pyrotinib combined with albumin-bound paclitaxel as first-line treatment for HER2-positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuvant trastuzumab therapy: The stage 1 results of a single-arm, phase 2 prospective clinical trial.