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Academic Journal

Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy.

  • Authors : Liu C; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.; Zhou F

Subjects: B7-H1 Antigen*/B7-H1 Antigen*/B7-H1 Antigen*/antagonists & inhibitors ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Programmed Cell Death 1 Receptor*/Programmed Cell Death 1 Receptor*/Programmed Cell Death 1 Receptor*/antagonists & inhibitors

  • Source: British journal of pharmacology [Br J Pharmacol] 2021 Jul; Vol. 178 (13), pp. 2651-2670. Date of Electronic Publication: 2021 May 04.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review).

  • Authors : Kong X; Integrated Traditional Chinese and Western Medicine Laboratory, College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P.R. China.; Lu P

Subjects: B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*genetics ; Immune Checkpoint Inhibitors/Immune Checkpoint Inhibitors/Immune Checkpoint Inhibitors/*therapeutic use ; Neoplasms/Neoplasms/Neoplasms/*therapy

  • Source: Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 24.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.

  • Authors : Liu C; Alibaba Research Center for Complexity Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Zhao J

Subjects: Gene Regulatory Networks*; Computational Biology/Computational Biology/Computational Biology/*methods ; Neoplasms/Neoplasms/Neoplasms/*genetics

  • Source: PLoS computational biology [PLoS Comput Biol] 2020 Feb 26; Vol. 16 (2), pp. e1007701. Date of Electronic Publication: 2020 Feb 26 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The role of necroptosis in cancer biology and therapy.

  • Authors : Gong Y; Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

Subjects: Gene Regulatory Networks* ; Necroptosis*; Neoplasms/Neoplasms/Neoplasms/*metabolism

  • Source: Molecular cancer [Mol Cancer] 2019 May 23; Vol. 18 (1), pp. 100. Date of Electronic Publication: 2019 May 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity.

  • Authors : Liu C; Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, Hubei 443001, P.R. China.; Lu J

Subjects: Gene Expression Regulation, Neoplastic* ; Immunomodulation*; B7-H1 Antigen/B7-H1 Antigen/B7-H1 Antigen/*genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2017 Mar; Vol. 15 (3), pp. 1063-1070. Date of Electronic Publication: 2017 Jan 05.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol.

  • Authors : Ma L; Department of Immunology, School of Basic Medical Sciences, Binzhou Medical University, Yantai 264003, China.; Liu M

Subjects: Cannabidiol*/Cannabidiol*/Cannabidiol*/pharmacology ; Cannabidiol*/Cannabidiol*/Cannabidiol*/therapeutic use ; Cannabidiol*/Cannabidiol*/Cannabidiol*/chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 24; Vol. 29 (9). Date of Electronic Publication: 2024 Apr 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Exploration of lncRNA/circRNA-miRNA-mRNA network in patients with chronic atrophic gastritis in Tibetan plateau areas based on DNBSEQ-G99 RNA sequencing.

  • Authors : Pan W; Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guoxue Lane, Wuhou District, Chengdu, 610054, Sichuan, China.; Department of Health Management Center, The Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Chengdu, Sichuan, China.

Subjects: Gastritis, Atrophic*/Gastritis, Atrophic*/Gastritis, Atrophic*/genetics ; RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics ; Gene Regulatory Networks*

  • Source: Scientific reports [Sci Rep] 2024 Apr 22; Vol. 14 (1), pp. 9212. Date of Electronic Publication: 2024 Apr 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The impact of lipidome on breast cancer: a Mendelian randomization study.

  • Authors : Cao Y; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Badachu Road, Shijingshan, Beijing, 100144, China.; Ai M

Subjects: Lipidomics* ; Neoplasms*; Bayes Theorem

  • Source: Lipids in health and disease [Lipids Health Dis] 2024 Apr 15; Vol. 23 (1), pp. 109. Date of Electronic Publication: 2024 Apr 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X

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Academic Journal

Gentulizumab, a novel anti-CD47 antibody with potent antitumor activity and demonstrates a favorable safety profile.

  • Authors : Wang T; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People's Republic of China.; GeneScience Pharmaceuticals Co., Ltd, Changchun, 130012, Jilin, People's Republic of China.

Subjects: CD47 Antigen* ; Neoplasms*/Neoplasms*/Neoplasms*/pathology; Animals

  • Source: Journal of translational medicine [J Transl Med] 2024 Mar 01; Vol. 22 (1), pp. 220. Date of Electronic Publication: 2024 Mar 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

UHPLC-MS/MS Assay for Quantification of Legubicin, a Novel Doxorubicin-Based Legumain-Activated Prodrug, and Its Application to Pharmacokinetic and Tissue Distribution Studies.

  • Authors : Ma L; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.

Subjects: Prodrugs*/Prodrugs*/Prodrugs*/chemistry ; Neoplasms* ; Cysteine Endopeptidases*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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