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Academic Journal

Design, synthesis, and biological evaluation of phenylisoxazole-based histone deacetylase inhibitors.

  • Authors : Qin X; Department of Clinical Pharmacy, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.; Clinical Pharmacy, Henan Province Key Subjects of Medicine, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemical synthesis ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry

  • Source: PloS one [PLoS One] 2025 Nov 05; Vol. 20 (11), pp. e0334632. Date of Electronic Publication: 2025 Nov 05 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Histone deacetylase inhibitors sensitize glioblastoma models to temozolomide and reprogram immunosuppressive myeloid cells.

  • Authors : Tehrani GA; Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, USA.; Kubick RN

Subjects: Temozolomide*/Temozolomide*/Temozolomide*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy

  • Source: Scientific reports [Sci Rep] 2025 Oct 21; Vol. 15 (1), pp. 36804. Date of Electronic Publication: 2025 Oct 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Adverse drug reaction profiles of histone deacetylase inhibitors.

  • Authors : Begum R; School of Pharmacy, School of Health Sciences, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; Parsons JL

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/adverse effects ; Drug-Related Side Effects and Adverse Reactions*/Drug-Related Side Effects and Adverse Reactions*/Drug-Related Side Effects and Adverse Reactions*/epidemiology ; Drug-Related Side Effects and Adverse Reactions*/Drug-Related Side Effects and Adverse Reactions*/Drug-Related Side Effects and Adverse Reactions*/etiology

  • Source: Scientific reports [Sci Rep] 2025 Oct 14; Vol. 15 (1), pp. 35880. Date of Electronic Publication: 2025 Oct 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Metformin sensitizes triple-negative breast cancer to histone deacetylase inhibitors by targeting FGFR4.

  • Authors : Gu Z; Department of Breast Surgery, Shanghai Key Laboratory of Maternal-Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, No. 2699 West Gao-Ke Road, Shanghai, 201204, China.; Ye F

Subjects: Metformin*/Metformin*/Metformin*/pharmacology ; Metformin*/Metformin*/Metformin*/therapeutic use ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy

  • Source: Journal of biomedical science [J Biomed Sci] 2025 Mar 17; Vol. 32 (1), pp. 36. Date of Electronic Publication: 2025 Mar 17.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Academic Journal

Drug repositioning identifies histone deacetylase inhibitors that promote innate immunity in non-tuberculous mycobacterial infection.

  • Authors : Rodriguez-Carlos A; Medical Research Unit-Zacatecas, Mexican Institute for Social Security-IMSS, Zacatecas, Mexico.; Raúl A

Subjects: Immunity, Innate*/Immunity, Innate*/Immunity, Innate*/drug effects ; Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/immunology ; Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/microbiology

  • Source: Canadian journal of microbiology [Can J Microbiol] 2024 Jul 01; Vol. 70 (7), pp. 252-261. Date of Electronic Publication: 2024 Jun 10.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372707 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Class I and II Histone Deacetylase Inhibitors as Therapeutic Modulators of Dilated Cardiac Tissue-Derived Mesenchymal Stem/Stromal Cells.

  • Authors : Mikšiūnas R; Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariškių 5, LT-08406 Vilnius, Lithuania.; Labeit S

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 19; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Next-Generation HDAC Inhibitors: Advancing Zinc-Binding Group Design for Enhanced Cancer Therapy.

  • Authors : Hawash M; Department of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus 00433, Palestine.

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

  • Source: Cells [Cells] 2025 Dec 15; Vol. 14 (24). Date of Electronic Publication: 2025 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases.

  • Authors : Zhang LY; Department of Pediatrics, PICU, Shengjing Hospital of China Medical University, Shenyang, China.; Wang YY

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/drug therapy

  • Source: Cell proliferation [Cell Prolif] 2025 Dec; Vol. 58 (12), pp. e70077. Date of Electronic Publication: 2025 Jun 11.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Academic Journal

Design and synthesis of polymer nanoparticles with pH-responsive pan-HDAC inhibitor (C5) derived from norbornene block copolymers to increase C5 solubility and improve its targeted delivery to prostate cancer sites.

  • Authors : Mathew J; Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.; TMU Research Center of Drug Discovery, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.

Subjects: Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/drug therapy ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/pathology ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/metabolism

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2530557. Date of Electronic Publication: 2025 Jul 23.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies.

  • Authors : Wawruszak A; Department of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland.; Luszczki J

Subjects: Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/antagonists & inhibitors ; Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/metabolism ; Paclitaxel*/Paclitaxel*/Paclitaxel*/pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2458554. Date of Electronic Publication: 2025 Feb 12.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,419 results for ""Histone Deacetylase Inhibitors""