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Academic Journal

The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway.

  • Authors : Dong XL; Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.; Department of Neurorehabilitation, Tangshan People's Hospital, Tangshan, 063000, China.

Subjects: AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*metabolism ; Cerebral Hemorrhage/Cerebral Hemorrhage/Cerebral Hemorrhage/*metabolism ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Oct 05; Vol. 11 (1), pp. 19737. Date of Electronic Publication: 2021 Oct 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The combination of rolipram and cilostamide improved the developmental competence of cloned porcine embryos.

  • Authors : Tanga BM; Lab of Theriogenology, College of Veterinary Medicine, Chungnam National University, 99, Daehak-ro, Daejeon, 34134, Republic of Korea.; School of Veterinary Medicine, Hawassa University, Hawassa, Ethiopia.

Subjects: In Vitro Oocyte Maturation Techniques*/In Vitro Oocyte Maturation Techniques*/In Vitro Oocyte Maturation Techniques*/methods ; Oocytes*/Oocytes*/Oocytes*/metabolism; Animals

  • Source: Scientific reports [Sci Rep] 2023 Apr 07; Vol. 13 (1), pp. 5733. Date of Electronic Publication: 2023 Apr 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of phosphodiesterase-4 inhibitor rolipram on colonic hypermotility in water avoidance stress rat model.

  • Authors : Yuan F; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.; Ren H

Subjects: Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/chemically induced ; Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/drug therapy ; Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/metabolism

  • Source: Neurogastroenterology and motility [Neurogastroenterol Motil] 2022 Jul; Vol. 34 (7), pp. e14317. Date of Electronic Publication: 2022 Jan 17.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9432572 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Rolipram plays an anti-fibrotic effect in ligamentum flavum fibroblasts by inhibiting the activation of ERK1/2.

  • Authors : Wu L; Department of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai, 200003, People's Republic of China.; School of Pharmacy & School of Medicine, ChangZhou University, Changzhou, 213164, People's Republic of China.

Subjects: Ligamentum Flavum*/Ligamentum Flavum*/Ligamentum Flavum*/pathology; Fibroblasts/Fibroblasts/Fibroblasts/metabolism ; Fibrosis

  • Source: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2021 Sep 23; Vol. 22 (1), pp. 818. Date of Electronic Publication: 2021 Sep 23.Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474

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Academic Journal

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram.

  • Authors : Chen TC; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA. .; Chan N

Subjects: Monoterpenes*/Monoterpenes*/Monoterpenes*/chemistry; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Jan 17; Vol. 19 (1). Date of Electronic Publication: 2018 Jan 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents.

  • Authors : Gong MF; Department of Neuropharmacology and Novel Drug Discovery, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.; Department of Behavioral Medicine and Psychiatry, Blanchette Rockefeller Neurosciences Institute, West Virginia University Health Sciences Center, Morgantown, WV, 26506, USA.

Subjects: Alcohol Abstinence/Alcohol Abstinence/Alcohol Abstinence/*psychology ; Anxiety/Anxiety/Anxiety/*psychology ; Depression/Depression/Depression/*psychology

  • Source: Psychopharmacology [Psychopharmacology (Berl)] 2017 Oct; Vol. 234 (20), pp. 3143-3151. Date of Electronic Publication: 2017 Jul 27.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification and in vivo evaluation of a fluorine-18 rolipram analogue, [(18) F]MNI-617, as a radioligand for PDE4 imaging in mammalian brain.

  • Authors : Thomae D; Molecular NeuroImaging LLC, New Haven, CT, 06510, USA.; Morley TJ

Subjects: Fluorine Radioisotopes*; Brain/Brain/Brain/*diagnostic imaging ; Brain/Brain/Brain/*metabolism

  • Source: Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2016 May 15; Vol. 59 (5), pp. 205-13. Date of Electronic Publication: 2016 Mar 22.Publisher: Wiley Country of Publication: England NLM ID: 7610510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1344

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Academic Journal

Multistep continuous-flow synthesis of (R)- and (S)-rolipram using heterogeneous catalysts.

  • Authors : Tsubogo T; Department of Chemistry and Green &Sustainable Chemistry Social Cooperation Laboratory, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.; Oyamada H

Subjects: Chemistry Techniques, Synthetic/Chemistry Techniques, Synthetic/Chemistry Techniques, Synthetic/*instrumentation ; Chemistry Techniques, Synthetic/Chemistry Techniques, Synthetic/Chemistry Techniques, Synthetic/*methods ; Rolipram/Rolipram/Rolipram/*chemical synthesis

  • Source: Nature [Nature] 2015 Apr 16; Vol. 520 (7547), pp. 329-32.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Rolipram Protects Mice from Gram-negative Bacterium Escherichia coli-induced Inflammation and Septic Shock.

  • Authors : Lu X; Department of Pathophysiology and Key Laboratory of Proteomics of Guangdong Province, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.; Wang J

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Escherichia coli Infections/Escherichia coli Infections/Escherichia coli Infections/*complications ; Inflammation/Inflammation/Inflammation/*drug therapy

  • Source: Scientific reports [Sci Rep] 2020 Jan 13; Vol. 10 (1), pp. 175. Date of Electronic Publication: 2020 Jan 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.

  • Authors : Boomkamp SD; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.; McGrath MA

Subjects: Spinal Cord Injuries*/Spinal Cord Injuries*/Spinal Cord Injuries*/drug therapy ; Spinal Cord Injuries*/Spinal Cord Injuries*/Spinal Cord Injuries*/pathology; Acetylcysteine/Acetylcysteine/Acetylcysteine/*analogs & derivatives

  • Source: British journal of pharmacology [Br J Pharmacol] 2014 May; Vol. 171 (9), pp. 2385-98.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN: 1476-5381 (Electronic)

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  • 1-10 of  252 results for ""Rolipram""