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Are anaplastic lymphoma kinase (ALK) and O6-methylguanine- DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)?

Authors : Hiddinga, Birgitta; Zwaenepoel, Karen; Janssens, Annelies

Subjects: MGMT promoter methylation; Guanine; Lung Neoplasms

Source: Oncotarget, 13, 800-809. Impact Journals LLC

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RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells

Authors : Tailor, Krishma; Paul, Joseph; Ghosh, Somiranjan

Subjects: TNFα signal; DNA methylation; RASAL2

Source: Oncotarget

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Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR

Authors : Karen B. Chapman; Brandon W. Higgs

Subjects: epigenetics; Promoter; Methylation

Source: Oncotarget

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Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry

Authors : Cerapio, Juan Pablo; Marchio, Agnès; Cano, Luis ...

Subjects: DNA methylation; MESH: Cancer; [SDV]Life Sciences [q-bio]

Source: OncotargetOncotarget, 2021, 12 (5), pp.475-492. ⟨10.18632/oncotarget.27890⟩

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Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma

Authors : Yasuhito Tanaka; Tetsuya Ikemoto; Shinichiro Yamada

Subjects: 0301 basic medicine; Tumor suppressor gene; medicine.disease_cause

Source: Oncotarget

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Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma

Authors : Jeffrey S Kuerbitz; Derek S. Damron; Monica L Cales

Subjects: 0301 basic medicine; DNA methylation; Thapsigargin

Source: Oncotarget

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Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation

Authors : Melanie H. Kucherlapati

Subjects: 0301 basic medicine; DNA damage; proliferation

Source: Oncotarget

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IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells

Authors : David Gillatt; Anthony Koupparis; Zhen Tang

Subjects: 0301 basic medicine; proliferation; Biology

Source: OncotargetTang, Z, Gillatt, D, Koupparis, A, Holly, J M P & Perks, C M 2019, ' IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity

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SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection

Authors : Dirk Bauerschlag; Sarah Bringezu; Nadina Ortiz-Brüchle

Subjects: 0301 basic medicine; Oncology; medicine.medical_specialty

Source: Oncotarget

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Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing

Authors : Miguel Vizoso; Jacco van Rheenen

Subjects: Epigenetic Process; targeted DNA methylation; Methylation

Source: Oncotarget

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