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Induction of apoptosis by cannabidiol and its main metabolites in human Leydig cells.

Authors : Li, Yuxi¹ (AUTHOR); Li, Xilin² (AUTHOR); Cournoyer, Patrick³ (AUTHOR)

Subjects: *LEYDIG cells; *CANNABIS (Genus); *CANNABIDIOL

Source: Archives of Toxicology. Dec2023, Vol. 97 Issue 12, p3227-3241. 15p.

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Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis.

Authors : Tuli, Hardeep Singh¹ (AUTHOR); Kaur, Jagjit² (AUTHOR); Vashishth, Kanupriya³ (AUTHOR)

Subjects: *APOPTOSIS; *BIOLOGICAL systems; *CELL death

Source: Archives of Toxicology. Jan2023, Vol. 97 Issue 1, p103-120. 18p.

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Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway.

Authors : Zhang, Tianwei^1,2 (AUTHOR); Feng, Shanshan³ (AUTHOR); Li, Jiahuan³ (AUTHOR)

Subjects: *FARNESOID X receptor; *LIVER regeneration; *APOPTOSIS

Source: Archives of Toxicology. Jun2022, Vol. 96 Issue 6, p1829-1843. 15p.

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The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro.

Authors : Haasler, Lisa¹ (AUTHOR) ; Kondadi, Arun Kumar¹ (AUTHOR); Tsigaras, Thanos¹ (AUTHOR)

Subjects: *GOSSYPOL; *MELANOMA; *MITOCHONDRIA

Source: Archives of Toxicology. Apr2021, Vol. 95 Issue 4, p1349-1365. 17p.

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Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3.

Authors : Yin, Haiyan¹ (AUTHOR) ; Sun, Yinuo¹ (AUTHOR); Ya, Bailiu¹ (AUTHOR)

Subjects: *HAIR cells; *STAT proteins; *SPIRAL ganglion

Source: Archives of Toxicology. Sep2023, Vol. 97 Issue 9, p2477-2493. 17p.

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ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis.

Authors : Wang, Bingqing¹ (AUTHOR); Wang, Yue¹ (AUTHOR); Zhang, Jing¹ (AUTHOR)

Subjects: *NUCLEAR factor E2 related factor; *MEMBRANE lipids; *LIPIDS

Source: Archives of Toxicology. Jun2023, Vol. 97 Issue 6, p1439-1451. 13p.

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Transcriptome dynamics of alternative splicing events revealed early phase of apoptosis induced by methylparaben in H1299 human lung carcinoma cells.

Authors : Kim, Mi Jin¹ (AUTHOR); Kim, Chul-Hong¹ (AUTHOR); Seo, Young-Jin¹ (AUTHOR)

Subjects: *APOPTOSIS; *CELL cycle; *ANTIMICROBIAL preservatives

Source: Archives of Toxicology. Jan2020, Vol. 94 Issue 1, p127-140. 14p. 2 Charts, 7 Graphs.

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Academic Journal

NF-κB/mTOR-mediated autophagy can regulate diquat-induced apoptosis.

Authors : Park, Aeri¹; Koh, Hyun Chul^1,2,3

Subjects: *DIQUAT; *AUTOPHAGY; *APOPTOSIS

Source: Archives of Toxicology. May2019, Vol. 93 Issue 5, p1239-1253. 15p. 6 Graphs.

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The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.

Authors : Dias da Silva, Diana¹ (AUTHOR) ; Ferreira, Bárbara¹ (AUTHOR); Roque Bravo, Rita¹ (AUTHOR)

Subjects: *OXIDATIVE stress; *LIVER cells; *CELL membranes

Source: Archives of Toxicology. Sep2019, Vol. 93 Issue 9, p2617-2634. 18p. 2 Diagrams, 1 Chart, 6 Graphs.

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Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.

Authors : Pons, Miriam¹; Reichardt, Claudia M.²; Hennig, Dorle^3,4

Subjects: *NEPHROBLASTOMA; *APOPTOSIS; *CANCER chemotherapy

Source: Archives of Toxicology. Jun2018, Vol. 92 Issue 6, p2119-2135. 17p. 1 Diagram, 6 Graphs.

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Induction of apoptosis by cannabidiol and its main metabolites in human Leydig cells.

Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis.

Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway.

The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro.

Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3.

ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis.

Transcriptome dynamics of alternative splicing events revealed early phase of apoptosis induced by methylparaben in H1299 human lung carcinoma cells.

NF-κB/mTOR-mediated autophagy can regulate diquat-induced apoptosis.

The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.

Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.

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