Search Results

The PENDOR study: establishment of a panel of patient-derived tumor organoids from endometrial cancer to assess efficacy of PARP inhibitors.

• Authors : Gall, Gwenn Le^1,2 (AUTHOR); Cherifi, François^2,3 (AUTHOR); Divoux, Jordane^1,4,5 (AUTHOR)

• Source: BMC Cancer. 2/11/2025, Vol. 24, p1-9. 9p.

Record details

Characterization of the genomic landscape in liver oligometastatic NSCLC.

• Authors : Liao, Rongxin¹ (AUTHOR); Yi, Guangming^1,2 (AUTHOR); Shen, Lu³ (AUTHOR)

• Source: BMC Cancer. 1/16/2025, Vol. 25 Issue 1, p1-11. 11p.

Record details

Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays

• Authors : Nicola Bassi; Henrikke Nilsen Hovland; Kashif Rasheed

Subjects: Hereditary breast and ovarian cancer; BRCA1; Functional assay

• Source: BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)

Record details

Concordance between single-nucleotide polymorphism–based genomic instability assays and a next-generation sequencing–based homologous recombination deficiency test

• Authors : Razvan Cristescu; Xiao Qiao Liu; Gladys Arreaza

Subjects: BRCA; Loss of heterozygosity; Homologous recombination deficiency

• Source: BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)

Record details

IMAGENE trial: multicenter, proof-of-concept, phase II study evaluating the efficacy and safety of combination therapy of niraparib with PD-1 inhibitor in solid cancer patients with homologous recombination repair genes mutation

• Authors : Taigo Kato; Nobuaki Matsubara; Masaki Shiota

Subjects: Homologous recombination repair; Niraparib; PARP inhibitor

• Source: BMC Cancer, Vol 22, Iss 1, Pp 1-6 (2022)

Record details

Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer

• Authors : Hao Wen; Zheng Feng; Yutong Ma

Subjects: Homologous recombination deficiency; BRCA1/2; Platinum chemotherapy

• Source: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)

Record details

Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort

• Authors : Benjamin D. Leibowitz; Bonnie V. Dougherty; Joshua S. K. Bell

Subjects: Gene expression profiling; Diagnostic biomarkers; Homologous recombination

• Source: BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)

Record details

Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets

• Authors : Zhongwu Lai; Matthew Brosnan; Ethan S. Sokol

Subjects: Homologous recombination deficiency; Homologous recombination repair; Genomic loss of heterozygosity

• Source: BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

Record details

Homologous recombination proficiency in ovarian and breast cancer patients

• Authors : Justin Fortune Creeden; Nisha S. Nanavaty; Katelyn R. Einloth

Subjects: Ovarian cancer; Breast cancer; PARP inhibitor

• Source: BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)

Record details

The efficacy and safety of PARP inhibitors in mCRPC with HRR mutation in second-line treatment: a systematic review and bayesian network meta-analysis.

• Authors : Zhu, Qiyu¹ (AUTHOR); Chen, Junru¹ (AUTHOR); Liu, Haoyang¹ (AUTHOR)

• Source: BMC Cancer. 6/8/2024, Vol. 24 Issue 1, p1-10. 10p.

Record details