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Academic Journal

Pharmacokinetics, pharmacodynamics and urinary recovery of oral lysergic acid diethylamide administration in healthy participants.

Authors : Holze, Friederike^1,2 (AUTHOR); Erne, Livio^1,2 (AUTHOR); Duthaler, Urs^1,2 (AUTHOR)

Subjects: *LSD (Drug); *PHARMACOKINETICS; *PHARMACODYNAMICS

Source: British Journal of Clinical Pharmacology. Jan2024, Vol. 90 Issue 1, p200-208. 9p.

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Academic Journal

Pharmacokinetics, pharmacodynamics and safety of oral formulation (CG‐750) of ivaltinostat, a histone deacetylase inhibitor, compared to IV formulation (CG‐745).

Authors : Kim, Byungwook; Huh, Ki Young; Yu, Kyung‐Sang

Subjects: HISTONE deacetylase inhibitors; PHARMACODYNAMICS; PHARMACOKINETICS

Source: British Journal of Clinical Pharmacology; Apr2024, Vol. 90 Issue 4, p1103-1114, 12p

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Academic Journal

Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID‐19 intensive care unit patients.

Authors : Romano, Lorenzo G. R.¹ (AUTHOR) ; Hunfeld, Nicole G. M.^2,3 (AUTHOR); Kruip, Marieke J. H. A.¹ (AUTHOR)

Subjects: *PHARMACOKINETICS; *INTENSIVE care patients; *MONTE Carlo method

Source: British Journal of Clinical Pharmacology. May2023, Vol. 89 Issue 5, p1617-1628. 12p.

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Academic Journal

Pharmacokinetics, pharmacodynamics and safety of the novel C‐X‐C chemokine receptor 3 antagonist ACT‐777991: Results from the first‐in‐human study in healthy adults.

Authors : Boof, Marie‐Laure; Géhin, Martine; Voors‐Pette, Christine

Subjects: CHEMOKINE receptors; PHARMACODYNAMICS; PHARMACOKINETICS

Source: British Journal of Clinical Pharmacology; Feb2024, Vol. 90 Issue 2, p588-599, 12p

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Academic Journal

A first in man study to evaluate the safety, pharmacokinetics and pharmacodynamics of RP7214, a dihydroorotate dehydrogenase inhibitor in healthy subjects.

Authors : Nair, Ajit¹ (AUTHOR) ; Barde, Prajak J.¹ (AUTHOR); Routhu, Kasi V.¹ (AUTHOR)

Subjects: *DIHYDROOROTATE dehydrogenase; *PHARMACOKINETICS; *ACUTE myeloid leukemia

Source: British Journal of Clinical Pharmacology. Mar2023, Vol. 89 Issue 3, p1127-1138. 12p.

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Academic Journal

Population total and unbound pharmacokinetics and pharmacodynamics of ciprofol and M4 in subjects with various renal functions.

Authors : Liu, Shuai‐bing^1,2 (AUTHOR); Yao, Xia^1,2 (AUTHOR); Tao, Jun^1,2 (AUTHOR)

Subjects: *PHARMACODYNAMICS; *PHARMACOKINETICS; *PROTEIN binding

Source: British Journal of Clinical Pharmacology. Mar2023, Vol. 89 Issue 3, p1139-1151. 13p.

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Academic Journal

Viral clearance, pharmacokinetics and tolerability of ensovibep in patients with mild to moderate COVID‐19: A phase 2a, open‐label, single‐dose escalation study.

Authors : Prins, Manon L. M.¹ (AUTHOR); van der Plas, Johan L.^1,2 (AUTHOR) ; Vissers, Maurits F. J. M.^2,3 (AUTHOR)

Subjects: *PHARMACOKINETICS; *COVID-19; *VIRAL load

Source: British Journal of Clinical Pharmacology. Mar2023, Vol. 89 Issue 3, p1105-1114. 10p.

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Academic Journal

Population pharmacokinetics, pharmacodynamics and pharmacogenetics modelling of oxypurinol in Hmong adults with gout and/or hyperuricemia.

Authors : Wen, Ya‐Feng; Brundage, Richard C.; Roman, Youssef M.

Subjects: HMONG (Asian people); PHARMACODYNAMICS; PHARMACOKINETICS

Source: British Journal of Clinical Pharmacology; Oct2023, Vol. 89 Issue 10, p2964-2976, 13p

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Academic Journal

Pharmacokinetics, pharmacodynamics and safety of BAY 2433334, a novel activated factor XI inhibitor, in healthy volunteers: A randomized phase 1 multiple‐dose study.

Authors : Kubitza, Dagmar¹ (AUTHOR) ; Heckmann, Michael¹ (AUTHOR); Distler, Jana² (AUTHOR)

Subjects: *PHARMACODYNAMICS; *PHARMACOKINETICS; *VOLUNTEERS

Source: British Journal of Clinical Pharmacology. Jul2022, Vol. 88 Issue 7, p3447-3462. 16p.

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Academic Journal

Pharmacokinetics, pharmacodynamics and safety assessment of multiple doses of soticlestat in healthy volunteers.

Authors : Wang, Shining¹ (AUTHOR); Chen, Grace¹ (AUTHOR); Merlo Pich, Emilio² (AUTHOR)

Subjects: *CHOLESTEROL hydroxylase; *PHARMACOKINETICS; *PHARMACODYNAMICS

Source: British Journal of Clinical Pharmacology. Jun2022, Vol. 88 Issue 6, p2899-2908. 10p.

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