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Academic Journal

Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARα/PPARγ coactivator-1α pathway.

Authors : Zhang C; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.; Department of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an, China.

Subjects: Aporphines/Aporphines/Aporphines/*pharmacology ; Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy ; Fatty Liver/Fatty Liver/Fatty Liver/*drug therapy

Source: British journal of pharmacology [Br J Pharmacol] 2018 Nov; Vol. 175 (22), pp. 4218-4228. Date of Electronic Publication: 2018 Oct 11.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity.

Authors : Nie T; Central Laboratory of the First Affiliated Hospital of Jinan University, Guangzhou, China.; Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

Subjects: Adipocytes/Adipocytes/Adipocytes/*drug effects ; Astragalus propinquus/Astragalus propinquus/Astragalus propinquus/*chemistry ; Isoflavones/Isoflavones/Isoflavones/*isolation & purification

Source: British journal of pharmacology [Br J Pharmacol] 2018 May; Vol. 175 (9), pp. 1439-1450. Date of Electronic Publication: 2018 Mar 14.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Rapamycin impairs HPD-induced beneficial effects on glucose homeostasis.

Authors : Chang GR; Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.; Division of Residual Control, Agricultural Chemicals and Toxic Substance Research Institute, Council of Agriculture, Taichung, Taiwan.

Subjects: Dietary Proteins/Dietary Proteins/Dietary Proteins/*pharmacology ; Glucose/Glucose/Glucose/*metabolism ; Homeostasis/Homeostasis/Homeostasis/*drug effects

Source: British journal of pharmacology [Br J Pharmacol] 2015 Aug; Vol. 172 (15), pp. 3793-804. Date of Electronic Publication: 2015 Jun 12.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Synthetic (+)-antroquinonol exhibits dual actions against insulin resistance by triggering AMP kinase and inhibiting dipeptidyl peptidase IV activities.

Authors : Hsu CY; Institute of Biotechnology, National Dong-Hwa University, Hualien, Taiwan; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan.

Subjects: AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*metabolism ; Dipeptidyl-Peptidase IV Inhibitors/Dipeptidyl-Peptidase IV Inhibitors/Dipeptidyl-Peptidase IV Inhibitors/*pharmacology ; Glucose Transporter Type 4/Glucose Transporter Type 4/Glucose Transporter Type 4/*metabolism

Source: British journal of pharmacology [Br J Pharmacol] 2015 Jan; Vol. 172 (1), pp. 38-49.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Novel coumarin modified GLP-1 derivatives with enhanced plasma stability and prolonged in vivo glucose-lowering ability.

Authors : Han J; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.; Sun L

Subjects: Hypoglycemic Agents*/Hypoglycemic Agents*/Hypoglycemic Agents*/pharmacokinetics ; Hypoglycemic Agents*/Hypoglycemic Agents*/Hypoglycemic Agents*/pharmacology ; Hypoglycemic Agents*/Hypoglycemic Agents*/Hypoglycemic Agents*/therapeutic use

Source: British journal of pharmacology [Br J Pharmacol] 2014 Dec; Vol. 171 (23), pp. 5252-64. Date of Electronic Publication: 2014 Sep 05.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Constitutive activation of AMPK α1 in vascular endothelium promotes high-fat diet-induced fatty liver injury: role of COX-2 induction.

Authors : Liang Y; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Huang B

Subjects: Diet, High-Fat*; AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*drug effects ; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*biosynthesis

Source: British journal of pharmacology [Br J Pharmacol] 2014 Jan; Vol. 171 (2), pp. 498-508.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue.

Authors : Wang M; Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China.; Gao XJ

Subjects: Adipose Tissue/Adipose Tissue/Adipose Tissue/*drug effects ; Genistein/Genistein/Genistein/*pharmacology ; Glucose/Glucose/Glucose/*metabolism

Source: British journal of pharmacology [Br J Pharmacol] 2013 Sep; Vol. 170 (2), pp. 328-40.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats.

Authors : Feigh M; Nordic Bioscience, Herlev, Denmark Diabetes Research Centre, Department of Endocrinology M, Odense University Hospital, Odense, Denmark. ; Andreassen KV

Subjects: Calcitonin/Calcitonin/Calcitonin/*administration & dosage ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*drug therapy ; Hyperglycemia/Hyperglycemia/Hyperglycemia/*drug therapy

Source: British journal of pharmacology [Br J Pharmacol] 2012 Sep; Vol. 167 (1), pp. 151-63.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis.

Authors : Massart J; INSERM, U991, Université de Rennes 1, Rennes, France.; Robin MA

Subjects: Fatty Liver/Fatty Liver/Fatty Liver/*metabolism ; Glucose/Glucose/Glucose/*metabolism ; Intestinal Absorption/Intestinal Absorption/Intestinal Absorption/*drug effects

Source: British journal of pharmacology [Br J Pharmacol] 2012 Mar; Vol. 165 (5), pp. 1361-74.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats.

Authors : Liu WJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, South Korea.; Jin HY

Subjects: Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*therapeutic use ; Peptides/Peptides/Peptides/*therapeutic use

Source: British journal of pharmacology [Br J Pharmacol] 2011 Nov; Vol. 164 (5), pp. 1410-20.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN:

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Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARα/PPARγ coactivator-1α pathway.

The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity.

Rapamycin impairs HPD-induced beneficial effects on glucose homeostasis.

Synthetic (+)-antroquinonol exhibits dual actions against insulin resistance by triggering AMP kinase and inhibiting dipeptidyl peptidase IV activities.

Novel coumarin modified GLP-1 derivatives with enhanced plasma stability and prolonged in vivo glucose-lowering ability.

Constitutive activation of AMPK α1 in vascular endothelium promotes high-fat diet-induced fatty liver injury: role of COX-2 induction.

Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue.

Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats.

Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis.

Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats.